Based on the fact that a search for influenza antivirals among nucleoside analogues has
drawn very little attention of chemists, the present study reports the synthesis of a series of 1 …

A series of 5′-phosphorylated (dialkyl phosphates, diaryl phosphates, phosphoramidates,
H-phosphonates, phosphates) 1, 2, 3-triazolyl nucleoside analogues in which the 1, 2, 3 …

In order to develop a new generation of biocides with a wide spectrum of activities
suppressing both bacteria and fungi, we have synthesized a representative library of novel …

Due to their versatile biological activity, Azoles are widely studied in pharmacochemistry. It is
possible to use them in many applications and in studies aimed at discovering antiparasitic …

The rapid increase in the antibiotic resistance of microorganisms, capable of causing
diseases in humans as destroying cultural heritage sites, is a great challenge for modern …

The emergence of drug‐resistant strains of pathogenic microorganisms necessitates the
creation of new drugs. A series of uridine derivatives containing an extended substituent at …

The emergence of drug-resistant strains of pathogenic microorganisms necessitates the
creation of new drugs. In order to find new compounds that effectively inhibit the growth of …

Tuberculosis (TB) is the oldest human infection disease. Mortality from TB significantly
decreased in the 20th century, because of vaccination and the widespread use of antibiotics …

Abstract A series of novel 1, 2, 3-triazolyl nucleoside analogues was synthesized via the
CuAAC reaction of N1-alkynyl uracil, 6-methyluracil, 3, 6-dimethyl uracil, thymine and …

Recently we have synthesized a set of pyrimidine nucleoside derivatives bearing extended
alkyltriazolylmethyl substituents at position 5 of the nucleic base, and showed their …