Early-onset colorectal cancer: initial clues and current views
Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in
patients< 50 years old) has increased at an alarming rate. Although robust and scientifically …
patients< 50 years old) has increased at an alarming rate. Although robust and scientifically …
Desulfovibrio in the Gut: The Enemy within?
SB Singh, A Carroll-Portillo, HC Lin - Microorganisms, 2023 - mdpi.com
Desulfovibrio (DSV) are sulfate-reducing bacteria (SRB) that are ubiquitously present in the
environment and as resident commensal bacteria within the human gastrointestinal tract …
environment and as resident commensal bacteria within the human gastrointestinal tract …
Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites
Objective Non-alcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma
(HCC) is an increasing healthcare burden worldwide. We examined the role of dietary …
(HCC) is an increasing healthcare burden worldwide. We examined the role of dietary …
Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping
Background & Aims Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes (T2D) and
obesity are epidemiologically correlated with each other but the causal inter-relationships …
obesity are epidemiologically correlated with each other but the causal inter-relationships …
Oat phenolic compounds regulate metabolic syndrome in high fat diet-fed mice via gut microbiota
L Dong, C Qin, Y Li, Z Wu, L Liu - Food Bioscience, 2022 - Elsevier
This study aimed to better understand the beneficial effect of oat phenolic compounds (OPC)
in improving metabolic syndrome via regulating metabolites and gut microbiota composition …
in improving metabolic syndrome via regulating metabolites and gut microbiota composition …
[HTML][HTML] Animal models of NAFLD from a hepatologist's point of view
D Jahn, S Kircher, HM Hermanns, A Geier - Biochimica et Biophysica Acta …, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disorder closely linked to obesity,
hyperlipidemia and type 2 diabetes and is increasingly recognized as a major health …
hyperlipidemia and type 2 diabetes and is increasingly recognized as a major health …
Bile acid receptors and the gut–liver axis in nonalcoholic fatty liver disease
R Xue, L Su, S Lai, Y Wang, D Zhao, J Fan, W Chen… - Cells, 2021 - mdpi.com
The prevalence of nonalcoholic fatty liver disease (NAFLD) has been significantly increased
due to the global epidemic of obesity. The disease progression from simple steatosis (NAFL) …
due to the global epidemic of obesity. The disease progression from simple steatosis (NAFL) …
Lactobacillus brevis DM9218 ameliorates fructose-induced hyperuricemia through inosine degradation and manipulation of intestinal dysbiosis
H Wang, L Mei, Y Deng, Y Liu, X Wei, M Liu, J Zhou… - Nutrition, 2019 - Elsevier
Objective High fructose consumption exacerbates purine degradation and intestinal
dysbiosis, which are closely related to the development of hyperuricemia. Probiotics are …
dysbiosis, which are closely related to the development of hyperuricemia. Probiotics are …
Porcine models for studying complications and organ crosstalk in diabetes mellitus
The worldwide prevalence of diabetes mellitus and obesity is rapidly increasing not only in
adults but also in children and adolescents. Diabetes is associated with macrovascular …
adults but also in children and adolescents. Diabetes is associated with macrovascular …
Large animal models of heart failure: a translational bridge to clinical success
Preclinical large animal models of heart failure (HF) play a critical and expanding role in
translating basic science findings to the development and clinical approval of novel …
translating basic science findings to the development and clinical approval of novel …