The daily removal of billions of apoptotic cells in the human body via the process of
efferocytosis is essential for homeostasis. To allow for this continuous efferocytosis, rapid …

Innate and adaptive immunity represent a harmonic counterbalanced system involved in the
induction, progression, and possibly resolution of the inflammatory reaction that characterize …

Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours
are known as tumour-associated macrophages (TAMs). These specialized immune cells …

Macrophages are the gatekeepers of intestinal immune homeostasis as they discriminate
between innocuous antigens and potential pathogens to maintain oral tolerance. However …

The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …

Macrophages play an important role in a wide variety of physiologic and pathologic
processes. Plasticity and functional polarization are hallmarks of macrophages …

Macrophages are heterogeneous and their phenotype and functions are regulated by the
surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) …

To define the cell populations that drive joint inflammation in rheumatoid arthritis (RA), we
applied single-cell RNA sequencing (scRNA-seq), mass cytometry, bulk RNA sequencing …

Background Traumatic brain injury (TBI) is a leading cause of death and disability
worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events …

Macrophages are extremely heterogeneous and plastic cells with an important role not only
in physiological conditions, but also during inflammation (both for initiation and resolution) …