Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and
adaptive immune systems, mediating inflammation in response to a wide range of stimuli …

The production of inflammatory proteins by the innate immune system is a tightly
orchestrated procedure that allows the body to efficiently respond to exogenous and …

Receptor‐type protein tyrosine phosphatase, receptor type D (PTPRD) has likely roles as a
neuronal cell adhesion molecule and synaptic specifier. Interest in its neurobiology and …

Protein phosphatases are major regulators of signal transduction and they are involved in
key cellular mechanisms such as proliferation, differentiation, and cell survival. Here we …

A substantial number of individuals have long-lasting adverse effects from a traumatic brain
injury (TBI). Depression is one of these long-term complications that influences many …

Abstract Neuroligin 3 (NLGN3) and neurexins (NRXNs) constitute a canonical transsynaptic
cell-adhesion pair, which has been implicated in autism. In autism spectrum disorder (ASD) …

Trans-synaptic cell-adhesion molecules are critical for governing various stages of synapse
development and specifying neural circuit properties via the formation of multifarious …

The IL-1 family of cytokines and receptors are critical regulators of inflammation. Within the
IL-1 family and in contrast to its IL-1 and IL-18 subfamilies, the IL-36 subfamily is still poorly …

LAR-type receptor phosphotyrosine-phosphatases (LAR-RPTPs) are presynaptic adhesion
molecules that interact trans-synaptically with multitudinous postsynaptic adhesion …

Synaptic adhesion molecules regulate diverse aspects of synapse development and
plasticity. SALM3 is a PSD-95-interacting synaptic adhesion molecule known to induce …