The spinocerebellar ataxias (SCAs) are a genetically heterogeneous group of autosomal
dominantly inherited progressive disorders, the clinical hallmark of which is loss of balance …

Spinocerebellar ataxia (SCA) is a heterogeneous group of neurodegenerative ataxic
disorders with autosomal dominant inheritance. We aim to provide an update on the recent …

The dominantly inherited spinocerebellar ataxias (SCAs) are a large and diverse group of
neurodegenerative diseases. The most prevalent SCAs (SCA1, SCA2, SCA3, SCA6 and …

Cerebellar ataxias constitute a heterogeneous group of disorders that result in impaired
speech, uncoordinated limb movements, and impaired balance, often ultimately resulting in …

The genetically heterozygous spinocerebellar ataxias are all characterized by cerebellar
atrophy and pervasive Purkinje Cell degeneration. Up to date, more than 35 functionally …

Chorea is defined by the presence of abnormal, involuntary, continuous, random
movements that results from a number of autoimmune, hereditary, vascular, metabolic, drug …

The hypothalamus has a vital role in controlling food intake and energy homeostasis; its
activity is modulated by neuropeptides and endocrine factors. Mesencephalic astrocyte …

Spinocerebellar ataxias (SCAs) are a heterogenous group of neurodegenerative disorders
which commonly inherited in an autosomal dominant manner. They cause muscle …

Cerebellar ataxia is a clinically heterogeneous group of disorders, which includes several
well-characterized genetic diseases as well as sporadic ataxias. The pathophysiology of …

Abstract Background Spinocerebellar ataxia 17 (SCA17) belongs to the family of
neurodegenerative diseases caused by polyglutamine (polyQ) expansion. In SCA17, polyQ …