Drug resistance remains a significant challenge in cancer treatment. Recently, the
interactions among various cell types within the tumor microenvironment (TME) have …

Mesenchymal stem/stromal cells (MSCs) encompass a heterogeneous population of
fibroblastic progenitor cells that reside in multiple tissues around the body. They are …

Background: Gastric cancer remains the third most common cause of cancer-related death
worldwide. The development of novel therapeutic strategies for gastric cancer requires a …

Metastatic cancer is largely incurable and is the main cause of cancer-related deaths. The
metastatic microenvironment facilitates formation of metastases. Cancer-associated …

Early apoptosis of grafted islets is one of the main factors affecting the efficacy of islet
transplantation. The combined transplantation of islet cells and bone marrow mesenchymal …

Background: Skin cutaneous melanoma (SKCM) is one of the most common cutaneous
malignancies, which incidence is increasing. Cuproptosis is a new type of programming cell …

Introduction Tendinopathy, the most common form of chronic tendon disorder, leads to
persistent tendon pain and loss of function. Profiling the heterogeneous cellular composition …

Background Snail family transcriptional repressor 2 (SNAI2) is a transcription factor that
induces epithelial to mesenchymal transition in neoplastic epithelial cells. It is closely related …

The role of mesenchymal stem cells (MSCs) in the breast tumor microenvironment (TME) is
significant and multifaceted. MSCs are recruited to breast tumor sites through molecular …

The scaffold protein PEAK1 acts downstream of integrin adhesion complexes and the
epidermal growth factor receptor, orchestrating signaling events that control cell proliferation …