Plasma inflammatory biomarkers in cerebral small vessel disease: A review

S Wan, C Dandu, G Han, Y Guo, Y Ding… - CNS neuroscience & …, 2023 - Wiley Online Library
Cerebral small vessel disease (CSVD) is a group of pathological processes affecting small
arteries, arterioles, capillaries, and small veins of the brain. It is one of the most common …

[HTML][HTML] The link between hyperhomocysteinemia and hypomethylation: Implications for cardiovascular disease

M Barroso, DE Handy, R Castro - … of Inborn Errors of Metabolism and …, 2019 - SciELO Brasil
Increased levels of homocysteine have been established as a risk factor for cardiovascular
disease (CVD) by mechanisms still incompletely defined. S-Adenosylhomocysteine (SAH) is …

[HTML][HTML] S-adenosylhomocysteine induces inflammation through NFkB: A possible role for EZH2 in endothelial cell activation

M Barroso, D Kao, HJ Blom, IT de Almeida… - Biochimica et biophysica …, 2016 - Elsevier
S-adenosylhomocysteine (SAH) can induce endothelial dysfunction and activation,
contributing to atherogenesis; however, its role in the activation of the inflammatory mediator …

Synergistic effects of danshen (salvia miltiorrhiza radix et rhizoma) and sanqi (notoginseng radix et rhizoma) combination in inhibiting inflammation mediators in …

X Zhou, V Razmovski-Naumovski… - BioMed Research …, 2016 - Wiley Online Library
Aims. This study aims to investigate the possible synergistic interactions of the Danshen‐
Sanqi combination on vascular disease via their anti‐inflammatory activities. Methods. Nine …

Diet-Induced Severe Hyperhomocysteinemia Promotes Atherosclerosis Progression and Dysregulates the Plasma Metabolome in Apolipoprotein-E-Deficient Mice

SG Andrews, AM Koehle, D Paudel, T Neuberger… - Nutrients, 2024 - mdpi.com
Atherosclerosis and resulting cardiovascular disease are the leading causes of death in the
US. Hyperhomocysteinemia (HHcy), or the accumulation of the intermediate amino acid …

Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression

M Barroso, C Florindo, H Kalwa, Z Silva… - Journal of Biological …, 2014 - ASBMB
S-Adenosylhomocysteine (SAH) is a negative regulator of most methyltransferases and the
precursor for the cardiovascular risk factor homocysteine. We have previously identified a …

[HTML][HTML] Homocysteine, paraoxonase-1 and vascular endothelial dysfunction: Omnibus viis romam pervenitur

E Eren, HY Ellidag, O Aydin… - Journal of Clinical and …, 2014 - ncbi.nlm.nih.gov
Increased oxidative stress, alterations of lipid metabolism and induction of thrombosis have
been suggested to be pathogenic links which are present between hyperhomocysteinaemia …

Endothelial aquaporins and hypomethylation: Potential implications for atherosclerosis and cardiovascular disease

IV Da Silva, M Barroso, T Moura, R Castro… - International journal of …, 2018 - mdpi.com
Aquaporins (AQPs) are transmembrane channels that facilitate water and glycerol
permeation through cell membranes. Recently, the water channel AQP1 was suggested to …

The effect of nutritional ketosis on aquaporin expression in apolipoprotein E-deficient mice: potential implications for energy homeostasis

IV da Silva, S Gullette, C Florindo, NK Huang… - Biomedicines, 2022 - mdpi.com
Ketogenic diets (KDs) are very low-carbohydrate, very high-fat diets which promote
nutritional ketosis and impact energetic metabolism. Aquaporins (AQPs) are transmembrane …

Effect of yoga on serum homocysteine and nitric oxide levels in adolescent women with and without dysmenorrhea

LW Chien, HC Chang, CF Liu - The Journal of Alternative and …, 2013 - liebertpub.com
Background: The purpose of the present study is to explore the effect of yoga on the serum
levels of homocysteine and nitric oxide (NO) in a cohort of women with primary …