The body plan of Drosophila is determined to a large extent by homeotic genes, which specify the identity and spatial arrangement of the body segments. Homeotic genes share a …
D Weigel, G Jürgens, F Küttner, E Seifert, H Jäckle - Cell, 1989 - cell.com
The region-specific homeotic gene fork head (fkh) promotes terminal as opposed to segmental development in the Drosophila embryo. We have cloned the f&h region by …
W Driever, C Nüsslein-Volhard - Cell, 1988 - cell.com
The maternal gene bicoid (bcd) organizes anterior development in Drosophila. Its mRNA is localized at the anterior tip of the oocyte and early embryo. Antibodies raised against bcd …
The doublesex (dsx) gene regulates somatic sexual differentiation in both sexes in D. melanogaster. Two functional products are encoded by dsx: one product is expressed in …
JT Kadonaga, KR Carner, FR Masiarz, R Tjian - Cell, 1987 - cell.com
Transcription factor Spl is a protein present in mammalian cells that binds to GC box promoter elements and selectively activates mRNA synthesis from genes that contain …
R Bodmer - Development, 1993 - journals.biologists.com
The homeobox-containing gene tinman (msh-2, Development 110, 661-669) is expressed in the mesoderm primordium, and this expression requires the function of the mesoderm …
D Bohmann, TJ Bos, A Admon, T Nishimura, PK Vogt… - Science, 1987 - science.org
Nuclear oncogene products have the potential to induce alterations in gene regulation leading to the genesis of cancer. The biochemical mechanisms by which nuclear …
MP Scott, JW Tamkun, GW Hartzell III - Biochimica et Biophysica Acta (BBA) …, 1989 - Elsevier
'Homeotic'transformations are developmental anomalies in which one part of the body develops iiJ the likeness of another. Many cases of homeosis were described and the …
The mec. 3 gene is essential for proper differentiation of the set of six touch receptor neurons in C. elegans. In mutants lacking mec. 3 activity, the touch receptors express none of their …