The term" homeosis"(originally spelled" homoeosis") was proposed by Bateson (8) to
describe the transformation of one structure of the body into the homologous structure of …

The body plan of Drosophila is determined to a large extent by homeotic genes, which
specify the identity and spatial arrangement of the body segments. Homeotic genes share a …

The region-specific homeotic gene fork head (fkh) promotes terminal as opposed to
segmental development in the Drosophila embryo. We have cloned the f&h region by …

The maternal gene bicoid (bcd) organizes anterior development in Drosophila. Its mRNA is
localized at the anterior tip of the oocyte and early embryo. Antibodies raised against bcd …

The doublesex (dsx) gene regulates somatic sexual differentiation in both sexes in D.
melanogaster. Two functional products are encoded by dsx: one product is expressed in …

Transcription factor Spl is a protein present in mammalian cells that binds to GC box
promoter elements and selectively activates mRNA synthesis from genes that contain …

The homeobox-containing gene tinman (msh-2, Development 110, 661-669) is expressed in
the mesoderm primordium, and this expression requires the function of the mesoderm …

Nuclear oncogene products have the potential to induce alterations in gene regulation
leading to the genesis of cancer. The biochemical mechanisms by which nuclear …

'Homeotic'transformations are developmental anomalies in which one part of the body
develops iiJ the likeness of another. Many cases of homeosis were described and the …

The mec. 3 gene is essential for proper differentiation of the set of six touch receptor neurons
in C. elegans. In mutants lacking mec. 3 activity, the touch receptors express none of their …