Biofabricated tissues have found numerous applications in tissue engineering and
regenerative medicine in addition to the promotion of disease modeling and drug …

Cancer still ranks as a leading cause of mortality worldwide. Although considerable efforts
have been dedicated to anticancer therapeutics, progress is still slow, partially due to the …

Neuroblastoma is an extracranial solid tumor which develops in early childhood and still has
a poor prognosis. One strategy to increase cure rates is the identification of patient-specific …

Previous studies have developed vascularized tumor spheroid models to demonstrate the
impact of intravascular flow on tumor progression and treatment. However, these models …

Despite substantial advancements in development of cancer treatments, lack of
standardized and physiologically‐relevant in vitro testing platforms limit the early screening …

Neuroblastoma (NB) is the most common extracranial tumor in children resulting in
substantial morbidity and mortality. A deeper understanding of the NB tumor …

Clinically, cancer drug therapy is still dominated by chemotherapy drugs. Although the
emergence of targeted drugs has greatly improved the survival rate of patients with …

Genetic instability can be caused by external factors and may also be associated with
intracellular damage. At the same time, there is a large body of research investigating the …

Immunotherapy has revolutionized cancer treatment with the advent of advanced cell
engineering techniques aimed at targeted therapy with reduced systemic toxicity. However …

Cancer is a severe threat to human life and health and represents the main cause of death
globally. Drug therapy is one of the primary means of treating cancer; however, most …