Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all
aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids …

Dairy fat and its fatty acids (FAs) have been shown to possess pro-health properties that can
support health maintenance and disease prevention. In particular, branched-chain FAs …

Objective The consumption of an agrarian diet is associated with a reduced risk for many
diseases associated with a 'Westernised'lifestyle. Studies suggest that diet affects the gut …

Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that
regulate lipid biosynthesis and adipogenesis by controlling the expression of several …

Background & Aims The cause of Crohn's disease (CD) is unknown, but the current
hypothesis is that microbial or environmental factors induce gut inflammation in genetically …

Polyunsaturated fatty acids (PUFAs) can be classified in n− 3 fatty acids and n− 6 fatty acids,
and in westernized diet the predominant dietary PUFAs are n− 6 fatty acids. Both types of …

The T arget of R apamycin (TOR or mTOR) is a serine/threonine kinase that regulates
growth, development, and behaviors by modulating protein synthesis, autophagy, and …

It is widely appreciated that larvae of the nematode Caenorhabditis elegans arrest
development by forming dauer larvae in response to multiple unfavorable environmental …

The sterol regulatory element binding protein (SREBP) family of transcription activators are
critical regulators of cholesterol and fatty acid homeostasis,. We previously demonstrated …

The intestine is one of the major organs in C. elegans and is largely responsible for food
digestion and assimilation as well as the synthesis and storage of macromolecules. In …