Non-coding RNAs have distinct regulatory roles in the pathogenesis of joint diseases
including osteoarthritis (OA) and rheumatoid arthritis (RA). As the amount of high-throughput …

Intervertebral disc degeneration (IDD) and osteoarthritis (OA) affecting the facet joint of the
spine are biomechanically interdependent, typically occur in tandem, and have considerable …

Osteoarthritis (OA) is the most common degenerative joint disease in the world. Gene
therapy based on delivering microRNAs (miRNAs) into cells has potential for the treatment …

Objective In this review, we have highlighted the advances over the past year in genetics,
genomics and epigenetics in the field of osteoarthritis (OA). Methods A literature search of …

Osteoarthritis (OA) is a common articular degenerative disease characterized by loss of
cartilage matrix and subchondral bone sclerosis. Kartogenin (KGN) has been reported to …

Exosomes are the small extracellular vesicles secreted by cells for intercellular
communication. Exosomes are rich in therapeutic cargos such as microRNA (miRNA), long …

Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

Osteoarthritis (OA) is progressive disease characterised by cartilage degradation,
subchondral bone remodelling and inflammation of the synovium. The disease is associated …

Extracellular vesicles (EVs), including exosomes and microvesicles, are released by
numerous cell types. EVs are now acknowledged as playing a critical role in cell–cell …

Background: Osteoarthritis (OA) is a major factor causing pain and disability. Studies
performed to date have suggested that synovitis is possibly a critical OA-related pathological …