Respiratory syncytial virus infection in adults

HH Nam, MG Ison - bmj, 2019 - bmj.com
Human respiratory syncytial virus (RSV) belongs to the recently defined Pneumoviridae
family, Orthopneumovirus genus. It is a negative sense, single stranded RNA virus that …

Treatment options for COVID-19: a review

MJ Ali, M Hanif, MA Haider, MU Ahmed… - Frontiers in …, 2020 - frontiersin.org
Background: The recent COVID-19 pandemic sweeping the globe has caused great concern
worldwide. Due to the limited evidence available on the dynamics of the virus and effective …

Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

D Bojkova, K Klann, B Koch, M Widera, D Krause… - Nature, 2020 - nature.com
A new coronavirus was recently discovered and named severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Infection with SARS-CoV-2 in humans causes coronavirus …

Prevention and treatment of cancer-related infections, version 2.2016, NCCN clinical practice guidelines in oncology

LR Baden, S Swaminathan, M Angarone… - Journal of the National …, 2016 - jnccn.org
Infectious diseases are important causes of morbidity and mortality in patients with cancer.
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prevention and …

Viral pneumonia: etiologies and treatment

D Dandachi… - Journal of Investigative …, 2018 - journals.sagepub.com
Viral pathogens are increasingly recognized as a cause of pneumonia, in immunocompetent
patients and more commonly among immunocompromised. Viral pneumonia in adults could …

Respiratory syncytial virus infection in older adults: an under-recognized problem

AR Branche, AR Falsey - Drugs & aging, 2015 - Springer
Human respiratory syncytial virus (RSV) is an enveloped, single-stranded, negative-sense
RNA virus and member of the Paramyxoviridae family of the genus Pneumovirus that was …

Oral versus aerosolized ribavirin for the treatment of respiratory syncytial virus infections in hematopoietic cell transplant recipients

F Foolad, SL Aitken, TL Shigle, A Prayag… - Clinical Infectious …, 2019 - academic.oup.com
Background The use of oral ribavirin (RBV) for respiratory syncytial virus (RSV) infections is
not well studied. With the drastic increase in the cost of aerosolized RBV, we aimed to …

Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China

X Pan, L Dong, L Yang, D Chen, C Peng - Virus research, 2020 - Elsevier
The fight against the novel coronavirus pneumonia (namely COVID-19) that seriously harms
human health is a common task for all mankind. Currently, development of drugs against the …

Ribavirin: a drug active against many viruses with multiple effects on virus replication and propagation. Molecular basis of ribavirin resistance

S Beaucourt, M Vignuzzi - Current opinion in virology, 2014 - Elsevier
Highlights•A broad spectrum antiviral effective against virtually all viruses tested in
vitro.•Mechanism of action varies with virus and cell type.•Virus resistance often involves …

Antiviral treatments

MG Ison - Clinics in chest medicine, 2017 - chestmed.theclinics.com
A wide range of viruses can affect the respiratory tract; in general, these can be divided into
viruses for which the primary site of infection is the respiratory tract (classic respiratory …