Improved conventional and new approaches in the diagnosis of tuberculosis

B Dong, Z He, Y Li, X Xu, C Wang, J Zeng - Frontiers in Microbiology, 2022 - frontiersin.org
Tuberculosis (TB) is a life-threatening infectious disease caused by Mycobacterium
tuberculosis (M. tuberculosis). Timely diagnosis and effective treatment are essential in the …

Utility of Real‐Time Quantitative Polymerase Chain Reaction in Detecting Mycobacterium tuberculosis

Z Lv, M Zhang, H Zhang, X Lu - BioMed research international, 2017 - Wiley Online Library
This study aimed to assess the value of real‐time quantitative polymerase chain reaction
(RT‐qPCR) for the detection of Mycobacterium tuberculosis (MTB). Samples from 192 …

[PDF][PDF] Jayaprakash Ergonomic diagnostic tool based on chip mini RT-PCR for diagnosis of pulmonary and extra pulmonary tuberculosis

V Mangayarkarasi, P Sneka… - J. Pure Appl. Microbiol, 2019 - molbiodiagnostics.com
Diagnosis of Tuberculosis (TB) is a challenging problem with the currently available
conventional methods such as microscopy for Acid Fast Bacilli (AFB) and culture techniques …

Rapid tuberculosis diagnosis using reporter enzyme fluorescence

P Sule, R Tilvawala, T Mustapha… - Journal of clinical …, 2019 - Am Soc Microbiol
Tuberculosis is the most frequent cause of death in humans from a single infectious agent.
Due to low numbers of bacteria present in sputum during early infection, diagnosis does not …

[HTML][HTML] Comparison of the microwave-heated Ziehl-Neelsen stain and conventional Ziehl-Neelsen method in the detection of acid-fast bacilli in lymph node biopsies

GM Ahmed, ASA Mohammed, AA Taha… - … Journal of Medical …, 2019 - ncbi.nlm.nih.gov
BACKGROUND: Tuberculosis is a chronic inflammatory disease with lymphadenopathy
being the most common extra-pulmonary manifestation. The conventional Ziehl–Neelsen …

Stabilization of Tuberculosis Reporter Enzyme Fluorescence (REFtb) Diagnostic Reagents for Use at the Point of Care

M Lebedev, AB Benjamin, KJ Koster, KE Broyles… - Diagnostics, 2022 - mdpi.com
Tuberculosis is one of the most frequent causes of death in humans worldwide. One of the
primary reasons tuberculosis remains a public health threat is that diagnosis can take weeks …

Imaging Mycobacterium tuberculosis in mice with reporter enzyme fluorescence

R Sharan, HJ Yang, P Sule… - Journal of Visualized …, 2018 - pmc.ncbi.nlm.nih.gov
Reporter enzyme fluorescence (REF) utilizes substrates that are specific for enzymes
present in target organisms of interest for imaging or detection by fluorescence or …

Innovative tools and in vivo methods for tuberculosis drug discovery and development

RC Sommer - 2019 - infoscience.epfl.ch
Worldwide, tuberculosis (TB) is the leading cause of death due to a single infectious agent,
claiming 1.6 million human lives and causing> 10 million new cases in 2017 alone, mostly in …

Optical In Vivo Imaging in Tuberculosis Research

R Sharan, T Galbadage, P Saenkham, M Moule… - Tuberculosis Host …, 2019 - Springer
Tuberculosis remains one of the greatest challenges to global health, making the
development of novel diagnostics and therapeutics for tuberculosis a high priority. However …

[PDF][PDF] Comparison of the Microwave-Heated Ziehl-Neelsen Stain and Conventional Ziehl-Neelsen Method in the Detection of Acid-Fast Bacilli in Lymph Node …

GM Ahmed, AS Mohammed, AA Taha, AA Almatroudi… - 2019 - scienceopen.com
BACKGROUND: Tuberculosis is a chronic inflammatory disease with lymphadenopathy
being the most common extra-pulmonary manifestation. The conventional Ziehl–Neelsen …