Substance use disorders (SUDs) are conditions in which the use of legal or illegal
substances, such as nicotine, alcohol or opioids, results in clinical and functional …

Abstract Background and Aims Research has shown that alcohol use and common mental
disorders (CMDs) co‐occur; however, little is known about how the global prevalence of …

Liability to alcohol dependence (AD) is heritable, but little is known about its complex
polygenic architecture or its genetic relationship with other disorders. To discover loci …

Alcohol's impact on telomere length, a proposed marker of biological aging, is unclear. We
performed the largest observational study to date (in n= 245,354 UK Biobank participants) …

Background Depression has been associated with metabolic alterations, which adversely
impact cardiometabolic health. Here, a comprehensive set of metabolic markers …

Abstract Background and Aims Alcohol use disorders (AUD) are often comorbid with
depressive symptoms. Cohort studies on the association between AUD and subsequent …

BackgroundPoor mental health has consistently been associated with substance use
(smoking, alcohol drinking, cannabis use, and consumption of caffeinated drinks). To …

Introduction Major depressive disorder (MDD) is a leading global psychiatric disease. MDD
is highly comorbid with gastrointestinal abnormalities, such as gut motility dysfunction. An …

Alcohol use disorder (AUD) is defined by several symptom criteria, which can be dissected
further at the genetic level. Over the past several years, our understanding of the genetic …

Background While use of artificial intelligence (AI) in healthcare is increasing, little is known
about how patients view healthcare AI. Characterizing patient attitudes and beliefs about …