Actinobacteriophages: genomics, dynamics, and applications

GF Hatfull - Annual review of virology, 2020 - annualreviews.org
Actinobacteriophages are viruses that infect bacterial hosts in the phylum Actinobacteria.
More than 17,000 actinobacteriophages have been described and over 3,000 complete …

[HTML][HTML] The resurgence of phage-based therapy in the era of increasing antibiotic resistance: from research progress to challenges and prospects

NJ Anyaegbunam, CC Anekpo… - Microbiological …, 2022 - Elsevier
Phage therapy was implemented almost a century ago but was subsequently abandoned
when antibiotics emerged. However, the rapid emergence of drug-resistant, which has …

PhaTYP: predicting the lifestyle for bacteriophages using BERT

J Shang, X Tang, Y Sun - Briefings in Bioinformatics, 2023 - academic.oup.com
Bacteriophages (or phages), which infect bacteria, have two distinct lifestyles: virulent and
temperate. Predicting the lifestyle of phages helps decipher their interactions with their …

Bacteriophages, a new therapeutic solution for inhibiting multidrug-resistant bacteria causing wound infection: lesson from animal models and clinical trials

M Taati Moghadam, A Khoshbayan… - Drug design …, 2020 - Taylor & Francis
Wound infection kills a large number of patients worldwide each year. Staphylococcus
aureus, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa …

[HTML][HTML] Global trends and hotspots of phage therapy for bacterial infection: A bibliometric visualized analysis from 2001 to 2021

Z Maimaiti, Z Li, C Xu, J Chen, W Chai - Frontiers in Microbiology, 2023 - frontiersin.org
Background Antibiotic resistance is one of the main global threats to human health, and just
the development of new antimicrobial medications is not enough to solve the crisis. Phage …

Formulation strategies for bacteriophages to target intracellular bacterial pathogens

W Yan, P Banerjee, M Xu, S Mukhopadhyay… - Advanced Drug Delivery …, 2021 - Elsevier
Bacteriophages (Phages) are antibacterial viruses that are unaffected by antibiotic drug
resistance. Many Phase I and Phase II phage therapy clinical trials have shown acceptable …

Topically Applied Bacteriophage to Control Multi-Drug Resistant Klebsiella pneumoniae Infected Wound in a Rat Model

MS Fayez, TA Hakim, MM Agwa, M Abdelmoteleb… - Antibiotics, 2021 - mdpi.com
(Background): Multi-drug-resistant Klebsiella pneumoniae (MDR-KP) has steadily grown
beyond antibiotic control. Wound infection kills many patients each year, due to the entry of …

Bacteriophages of Mycobacterium tuberculosis, their diversity, and potential therapeutic uses: a review

F Zeynali kelishomi, S Khanjani, F Fardsanei… - BMC Infectious …, 2022 - Springer
Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tuberculosis) is a highly
infectious disease and worldwide health problem. Based on the WHO TB report, 9 million …

Accurate identification of bacteriophages from metagenomic data using Transformer

J Shang, X Tang, R Guo, Y Sun - Briefings in Bioinformatics, 2022 - academic.oup.com
Motivation Bacteriophages are viruses infecting bacteria. Being key players in microbial
communities, they can regulate the composition/function of microbiome by infecting their …

Applications of bacteriophages against intracellular bacteria

P Śliwka, M Ochocka… - Critical Reviews in …, 2022 - Taylor & Francis
Infectious diseases pose a significant threat to both human and animal populations.
Intracellular bacteria are a group of pathogens that invade and survive within the interior of …