[HTML][HTML] A review on the synthesis and application of naphthoquinone-based drugs

J Khan, A Rani, M Aslam, G Pandey, BN Pant - Results in Chemistry, 2023 - Elsevier
Naphthoquinones are secondary plant metabolites that are used to treat a variety of human
ailments in traditional medicine. In light of this, the synthesis of derivatives of …

[HTML][HTML] Current status of 1, 4-Naphthoquinones and their derivatives for wound healing

P Kumari, V Singh, V Kant, M Ahuja - European Journal of Medicinal …, 2024 - Elsevier
Cutaneous wounds are a major healthcare concern affecting millions of people as they fail
to heal properly and can result in life threatening conditions and high economic loss. Wound …

Organocatalytic atroposelective synthesis of naphthoquinone thioglycosides from aryl-naphthoquinones and thiosugars

Y Wu, WJ Zhou, L Yao, Y Niu, H Zhao… - Chemical …, 2023 - pubs.rsc.org
In this study, we report an organocatalytic formal coupling strategy for aryl-naphthoquinones
with thiosugars that provides straightforward access to the axially chiral naphthoquinone …

Gold/HNTf2-Cocatalyzed Asymmetric Annulation of Diazo-Alkynes: Divergent Construction of Atropisomeric Biaryls and Arylquinones

YB Wang, W Liu, T Li, Y Lu, YT Yu, HT Liu… - Journal of the …, 2024 - ACS Publications
Due to the inherent challenges posed by the linear coordination of gold (I) complexes,
asymmetric gold-catalyzed processes remain challenging, particularly in the atroposelective …

[HTML][HTML] Theoretical investigation of the effects of aldehyde substitution with pyran groups in D-π-A Dye on performance of DSSCs

SK Alghamdi, AI Aljameel, RK Hussein, K Al-Heuseen… - Molecules, 2024 - mdpi.com
This work investigated the substitution of the aldehyde with a pyran functional group in D-π-
aldehyde dye to improve cell performance. This strategy was suggested by recent work that …

Hybrids of 1, 4-Naphthoquinone with Thymidine Derivatives: Synthesis, Anticancer Activity, and Molecular Docking Study

M Kadela-Tomanek, K Krzykawski, A Halama… - Molecules, 2023 - mdpi.com
One of the most essential health problems is cancer, the first or second cause of death
worldwide. Head and neck cancers are hard to detect due to non-specific symptoms. The …

The current status on secondary metabolites produced by fungi of the genus Diplodia associated with plants

MM Salvatore, M Masi, A Andolfi - Phytochemistry Reviews, 2024 - Springer
Fungi of the genus Diplodia have a worldwide distribution and are typically associated with
plants. Diplodia is well‐known for the diseases it causes on economically and ecologically …

Novel Henna-Related Naphthazarine Photosensitizers for an Effective Photodynamic Therapy of Onychomycosis

J Baier, B Jansen, A Wenzel-Storjohann… - ACS Pharmacology & …, 2023 - ACS Publications
Onychomycosis caused by, eg, Trichophyton rubrum or Candida albicans is the most
common human nail disease with a worldwide prevalence of more than 10%. The …

Description of Some Methodologies for the Synthesis of 1, 4-Naphthoquinone Derivatives and Examples of their Biological Activity: A Review

SE Loredo-Carrillo, E Leyva… - Current Organic …, 2024 - benthamdirect.com
An alternative to finding new drugs for the treatment of various diseases is the chemical
modification of the structure of compounds of natural origin. Among them, naphthoquinones …

Identification of new leads against ubiquitin specific protease-7 (USP7): a step towards the potential treatment of cancers

S Javaid, S Zadi, M Awais, A Wahab, H Zafar… - RSC …, 2024 - pubs.rsc.org
Ubiquitin-specific protease-7 (USP7) is an important drug target as it regulates multiple
proteins and genes (such as MDM2 and p53) with roles in cancer progression. Its inhibition …