Globally, clear-cell renal cell carcinoma (ccRCC) represents the most prevalent type of
kidney cancer. Surgery plays a key role in the treatment of this cancer, although one third of …

Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Despite recent advances, the poor outcomes in renal cell carcinoma (RCC) suggest novel
therapeutics are needed. Ferroptosis is a form of regulated cell death, which may have …

Dietary methionine interventions are beneficial to apoptosis-inducing chemotherapy and
radiotherapy for cancer, while their effects on ferroptosis-targeting therapy and …

Ovarian cancer is the deadliest gynecologic cancer. Despite recent advances, clinical
outcomes remain poor, necessitating novel therapeutic approaches. To investigate …

Metabolic reprogramming is a prominent feature of clear cell renal cell carcinoma (ccRCC).
Here we investigated metabolic dependencies in a panel of ccRCC cell lines using nutrient …

Epstein–Barr virus (EBV) was the first oncogenic virus identified in humans. It is primarily
associated with multiple lymphoid and epithelial cancers, including nasopharyngeal …

Ferroptosis is a specialized iron-dependent cell death that is associated with lethal lipid
peroxidation. Modulation of ferroptosis may have therapeutic potential since it has been …

Cancer cells exhibit an abnormal amino acid metabolism and a dependence on specific
amino acids, which might provide potential targets for treating cancer patients. In this study …

Renal cell carcinoma (RCC) is one of the most common tumours of the urinary system, and
is insidious and not susceptible to chemoradiotherapy. As the most common subtype of RCC …