Metabolomics for investigating physiological and pathophysiological processes

DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

Shaping the leaf microbiota: plant–microbe–microbe interactions

V Chaudhry, P Runge, P Sengupta… - Journal of …, 2021 - academic.oup.com
The aerial portion of a plant, namely the leaf, is inhabited by pathogenic and non-pathogenic
microbes. The leaf's physical and chemical properties, combined with fluctuating and often …

Biofilms: Survival and defense strategy for pathogens

A Kumar, A Alam, M Rani, NZ Ehtesham… - International Journal of …, 2017 - Elsevier
Studies on biofilm related infections are gaining prominence owing to their involvement in
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …

The role of bacterial biofilms in chronic infections

T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …

Biofilm and Quorum sensing mediated pathogenicity in Pseudomonas aeruginosa

K Brindhadevi, F LewisOscar, E Mylonakis… - Process …, 2020 - Elsevier
The emergence of multidrug resistance has become an alarming and lifethreatening
phenomenon for humans. Various mechanisms are involved in the development of …

Quorum sensing and bacterial social interactions in biofilms

YH Li, X Tian - Sensors, 2012 - mdpi.com
Many bacteria are known to regulate their cooperative activities and physiological processes
through a mechanism called quorum sensing (QS), in which bacterial cells communicate …

Bacterial competition: surviving and thriving in the microbial jungle

ME Hibbing, C Fuqua, MR Parsek… - Nature reviews …, 2010 - nature.com
Most natural environments harbour a stunningly diverse collection of microbial species. In
these communities, bacteria compete with their neighbours for space and resources …

Applying insights from biofilm biology to drug development—can a new approach be developed?

T Bjarnsholt, O Ciofu, S Molin, M Givskov… - Nature reviews Drug …, 2013 - nature.com
Most of the research on bacterial pathogenesis has focused on acute infections, but much
less is known about the pathogenesis of infections caused by bacteria that grow as …

The cognitive cell: bacterial behavior reconsidered

P Lyon - Frontiers in microbiology, 2015 - frontiersin.org
Research on how bacteria adapt to changing environments underlies the contemporary
biological understanding of signal transduction (ST), and ST provides the foundation of the …

Chemical signaling involved in plant–microbe interactions

FO Chagas, R de Cassia Pessotti… - Chemical Society …, 2018 - pubs.rsc.org
Microorganisms are found everywhere, and they are closely associated with plants.
Because the establishment of any plant–microbe association involves chemical …