From bacterial killing to immune modulation: Recent insights into the functions of lysozyme

SA Ragland, AK Criss - PLoS pathogens, 2017 - journals.plos.org
Lysozyme is a cornerstone of innate immunity. The canonical mechanism for bacterial killing
by lysozyme occurs through the hydrolysis of cell wall peptidoglycan (PG). Conventional …

Wall teichoic acids of gram-positive bacteria

S Brown, JP Santa Maria Jr… - Annual review of …, 2013 - annualreviews.org
The peptidoglycan layers of many gram-positive bacteria are densely functionalized with
anionic glycopolymers known as wall teichoic acids (WTAs). These polymers play crucial …

Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform

X Wang, CD Thompson, C Weidenmaier… - Nature …, 2018 - nature.com
Secretion of extracellular vesicles (EVs), a process common to eukaryotes, archae, and
bacteria, represents a secretory pathway that allows cell-free intercellular communication …

Cell wall structure and function in lactic acid bacteria

MP Chapot-Chartier, S Kulakauskas - Microbial cell factories, 2014 - Springer
The cell wall of Gram-positive bacteria is a complex assemblage of glycopolymers and
proteins. It consists of a thick peptidoglycan sacculus that surrounds the cytoplasmic …

Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa

PA Bron, P Van Baarlen, M Kleerebezem - Nature Reviews …, 2012 - nature.com
Probiotic bacteria can modulate immune responses in the host gastrointestinal tract to
promote health. The genomics era has provided novel opportunities for the discovery and …

Envelope structures of Gram-positive bacteria

M Rajagopal, S Walker - Protein and sugar export and assembly in Gram …, 2017 - Springer
Gram-positive organisms, including the pathogens Staphylococcus aureus, Streptococcus
pneumoniae, and Enterococcus faecalis, have dynamic cell envelopes that mediate …

MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis

S Hussain, CN Wivagg, P Szwedziak, F Wong… - Elife, 2018 - elifesciences.org
MreB is essential for rod shape in many bacteria. Membrane-associated MreB filaments
move around the rod circumference, helping to insert cell wall in the radial direction to …

Cell shape dynamics during the staphylococcal cell cycle

JM Monteiro, PB Fernandes, F Vaz, AR Pereira… - Nature …, 2015 - nature.com
Staphylococcus aureus is an aggressive pathogen and a model organism to study cell
division in sequential orthogonal planes in spherical bacteria. However, the small size of …

How to get (a) round: mechanisms controlling growth and division of coccoid bacteria

MG Pinho, M Kjos, JW Veening - Nature reviews microbiology, 2013 - nature.com
Bacteria come in a range of shapes, including round, rod-shaped, curved and spiral cells.
This morphological diversity implies that different mechanisms exist to guide proper cell …

Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesis

JM Monteiro, AR Pereira, NT Reichmann, BM Saraiva… - Nature, 2018 - nature.com
Peptidoglycan is the main component of the bacterial wall and protects cells from the
mechanical stress that results from high intracellular turgor. Peptidoglycan biosynthesis is …