Malaria parasites are unicellular eukaryotic pathogens that develop through a complex
lifecycle involving two hosts, an anopheline mosquito and a vertebrate host. Throughout this …

Plasmodium parasites have a complex life cycle that includes development in the human
host as well as the Anopheles vector. Successful transmission of the parasite between its …

Lipid droplets (LDs) are organelles that are central to lipid and energy homeostasis across
all eukaryotes. In the malaria-causing parasite Plasmodium falciparum the roles of LDs in …

Onward transmission of Plasmodium falciparum from humans to mosquitoes is dependent
upon a specialised transmission stage called the gametocyte. Despite its critical role in …

Novel antimalarial compounds targeting both the pathogenic and transmissible stages of the
human malaria parasite, Plasmodium falciparum, would greatly benefit malaria elimination …

Serine/arginine-rich protein kinases (SRPKs) are cell cycle-regulated serine/threonine
protein kinases and are important regulators of splicing factors. In this study, we functionally …

Parasites, such as the malaria parasite P. falciparum, are critically dependent on host
nutrients. Interference with nutrient uptake can lead to parasite death and, therefore, serve …

Eukaryotic pathogens with an intracellular parasitic lifestyle are shielded from extracellular
threats during replication and growth. In addition to many nutrients, parasites scavenge host …

The human malaria parasite Plasmodium falciparum causes the most severe form of malaria
in endemic regions and is transmitted via mosquito bites. To better understand the biology of …

Malaria is one of the most important infectious diseases worldwide and represents a
persistent socio-economic burden on mankind. The disease is caused by the unicellular …