Lateral Deprotometallation‐Trapping Reactions on Methylated Pyridines, Quinolines and Quinoxalines Using Lithium Diethylamide
M Hasyeoui, PM Chapple, F Lassagne… - European Journal of …, 2023 - Wiley Online Library
The functionalization of methylated azines and diazines has aroused the interest of chemists
given the structural diversity that it affords. Hindered lithium dialkylamides have been used …
given the structural diversity that it affords. Hindered lithium dialkylamides have been used …
Use of lithium diisopropylamide in flow: operability and safety challenges encountered on a multigram scale
A workflow for the development of organometallic processes in flow was applied to
synthesize 1-(5-bromopyridin-2-yl)-2-methylpropan-2-ol, a pharmaceutical intermediate. Key …
synthesize 1-(5-bromopyridin-2-yl)-2-methylpropan-2-ol, a pharmaceutical intermediate. Key …