Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

Abstract Metal-organic frameworks (MOFs), comprised of organic ligands and metal
ions/metal clusters via coordinative bonds are highly porous, crystalline materials. Their …

Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …

Lipid-based drug delivery systems, or lipidic carriers, are being extensively employed to
enhance the bioavailability of poorly-soluble drugs. They have the ability to incorporate both …

Alginate is one of the natural polymers that are often used in drug‐and protein‐delivery
systems. The use of alginate can provide several advantages including ease of preparation …

Recent progress in protein-based nanomedicine, inspired by the success of Abraxane®
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …

Despite the critical breakthrough achieved by immune checkpoint blockade (ICB), the
clinical benefits are usually restricted by inefficient infiltration of immune cells and immune …

Starting with the enhanced permeability and retention (EPR) effect discovery, nanomedicine
has gained a crucial role in cancer treatment. The advances in the field have led to the …

Different strategies have been developed to overcome limitations of traditional
pharmacological treatments (biodegradation, low specificity, toxicity, side effects) …