Basic principles and emerging concepts in the redox control of transcription factors
R Brigelius-Flohé, L Flohé - Antioxidants & redox signaling, 2011 - liebertpub.com
Convincing concepts of redox control of gene transcription have been worked out for
prokaryotes and lower eukaryotes, whereas the knowledge on complex mammalian systems …
prokaryotes and lower eukaryotes, whereas the knowledge on complex mammalian systems …
Regulation and function of IKK and IKK-related kinases
H Hacker, M Karin - Science's STKE, 2006 - science.org
Members of the nuclear factor kappa B (NF-κB) family of dimeric transcription factors (TFs)
regulate expression of a large number of genes involved in immune responses …
regulate expression of a large number of genes involved in immune responses …
Inducibility of K immunoglobulin enhancer-binding protein NF-KB by a posttranslational mechanism
R Sen, D Baltimore - Cell, 1986 - cell.com
NF-KB is a nuclear protein, found only in cells that transcribe immunoglobulin light chain
genes, that interacts with a defined site in the K immunoglobulin enhancer. This protein can …
genes, that interacts with a defined site in the K immunoglobulin enhancer. This protein can …
Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling
AH Cornell-Bell, SM Finkbeiner, MS Cooper, SJ Smith - Science, 1990 - science.org
The finding that astrocytes possess glutamate-sensitive ion channels hinted at a previously
unrecognized signaling role for these cells. Now it is reported that cultured hippocampal …
unrecognized signaling role for these cells. Now it is reported that cultured hippocampal …
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.
QW Xie, Y Kashiwabara, C Nathan - Journal of Biological Chemistry, 1994 - ASBMB
The promoter of the murine gene encoding inducible nitric oxide synthase (iNOS) contains
an NF-kappa B site beginning 55 base pairs upstream of the TATA box, designated NF …
an NF-kappa B site beginning 55 base pairs upstream of the TATA box, designated NF …
IκB: a specific inhibitor of the NF-κB transcription factor
PA Baeuerle, D Baltimore - Science, 1988 - science.org
In cells that do not express immunoglobulin kappa light chain genes, the kappa enhancer
binding protein NF-κB is found in cytosolic fractions and exhibits DNA binding activity only in …
binding protein NF-κB is found in cytosolic fractions and exhibits DNA binding activity only in …
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
Human immunodeficiency virus type 1 (HIV-1) gene expression is modulated by both viral
and cellular factors. A regulatory element in the HIV-1 long terminal repeat known as TAR …
and cellular factors. A regulatory element in the HIV-1 long terminal repeat known as TAR …
The activation antigen CD69
SF Ziegler, F Ramsdell, MR Alderson - Stem cells, 1994 - academic.oup.com
One of the earliest cell surface antigens expressed by T cells following activation is CD69,
which is detectable within one h of ligation of the T cell receptor/CD3 complex. Once …
which is detectable within one h of ligation of the T cell receptor/CD3 complex. Once …
The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain
ABSTRACT TTF-1, a homeodomain-containing transcription factor, which is required for the
specific expression of the thyroglobulin and thyroperoxidase gene promoters in …
specific expression of the thyroglobulin and thyroperoxidase gene promoters in …
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo
MH Rosner, MA Vigano, K Ozato, PM Timmons… - Nature, 1990 - nature.com
The murine oct-3 gene encodes a transcription factor containing a POU-specific domain and
a homeodomain. In marked contrast to other homeodomain-encoding genes, oct-3 is …
a homeodomain. In marked contrast to other homeodomain-encoding genes, oct-3 is …