Non-coding RNAs in enzalutamide resistance of castration-resistant prostate cancer

K Gao, X Li, J Ni, B Wu, J Guo, R Zhang, G Wu - Cancer Letters, 2023 - Elsevier
Enzalutamide (Enz) is a next-generation androgen receptor (AR) antagonist used to treat
castration-resistant prostate cancer (CRPC). Unfortunately, the relapsing nature of CRPC …

miRNAs and androgen deprivation therapy for prostate cancer

MY Konoshenko, OE Bryzgunova… - Biochimica et Biophysica …, 2021 - Elsevier
Androgen deprivation therapy (ADT) is mainly used for the treatment of advanced, metastatic
or recurrent prostate cancer (PCa). However, patients progress to ADT resistance and …

[PDF][PDF] m6A modification of circSPECC1 suppresses RPE oxidative damage and maintains retinal homeostasis

X Chen, Y Wang, JN Wang, QC Cao, RX Sun, HJ Zhu… - Cell reports, 2022 - cell.com
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the
elderly population with unclear pathogenic mechanism. Herein, we detect downregulated …

[HTML][HTML] Targeting androgen receptor (AR) with antiandrogen Enzalutamide increases prostate cancer cell invasion yet decreases bladder cancer cell invasion via …

G Deng, R Wang, Y Sun, CP Huang, S Yeh… - Cell Death & …, 2021 - nature.com
Androgen-deprivation therapy (ADT) via targeting androgens/androgen receptor (AR)
signals may suppress cell proliferation in both prostate cancer (PCa) and bladder cancer …

Cancer stem cells in prostate cancer: implications for targeted therapy

R Leão, C Domingos, A Figueiredo, R Hamilton… - Urologia …, 2017 - karger.com
Prostate cancer (PCa) is the most frequently diagnosed cancer in men and the second most
common cause of cancer-related mortality among men in the developed world …

Highly efficient electrochemiluminescence resonance energy transfer system in one nanostructure: its application for ultrasensitive detection of MicroRNA in cancer …

Z Li, Z Lin, X Wu, H Chen, Y Chai, R Yuan - Analytical chemistry, 2017 - ACS Publications
The electrochemiluminesce (ECL) efficiency of luminous emitter can be enhanced by the
means of electrochemiluminesce resonance energy transfer (ECL-RET) with a matched …

Retracted: Effects of miR‐145‐5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways

S Liu, G Gao, D Yan, X Chen, X Yao, S Guo… - Cancer …, 2017 - Wiley Online Library
We aimed to detect the effects of miR‐145‐5p on the cell proliferation, apoptosis, migration,
and invasion in NRAS‐mutant, BRAF‐mutant, and wild‐type melanoma cells, in order to …

Computer-aided biomarker discovery for precision medicine: data resources, models and applications

Y Lin, F Qian, L Shen, F Chen, J Chen… - Briefings in …, 2019 - academic.oup.com
Biomarkers are a class of measurable and evaluable indicators with the potential to predict
disease initiation and progression. In contrast to disease-associated factors, biomarkers …

Decreased miR-218–5p levels as a serum biomarker in bone metastasis of prostate cancer

P Peng, T Chen, Q Wang, Y Zhang, F Zheng… - Oncology research and …, 2019 - karger.com
Background: miR-218–5p is an extensively studied microRNA (miRNA) in prostate cancer
(PCa). However, the clinical significance and biological role of miR-218–5p in bone …

LncRNA DGCR5 represses the development of hepatocellular carcinoma by targeting the miR‐346/KLF14 axis

YG Wang, J Liu, M Shi, FX Chen - Journal of cellular physiology, 2019 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) are a class of regulatory noncoding RNAs. Emerging
evidence highlights the critical roles of lncRNAs in the progression of hepatocellular …