Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …

Over the last decade, the introduction of omics technologies–especially high-throughput
genomics and metabolomics–has contributed significantly to our understanding of the role of …

Transfusion of red blood cells (RBCs) is one of the most valuable and widespread
treatments in modern medicine. Lifesaving RBC transfusions are facilitated by the cold …

Redox imbalance and oxidative stress have emerged as generative causes of the structural
and functional degradation of red blood cells (RBC) that happens during their hypothermic …

Background: Blood transfusion is a life-saving intervention for millions of recipients
worldwide. Over the last 15 years, the advent of high-throughput, affordable omics …

Our aim is to present an updated overview of the erythrocyte metabolism highlighting its
richness and complexity. We have manually collected and connected the available …

Peroxiredoxin 2 (Prdx2) is the third most abundant erythrocyte protein. It was known
previously as calpromotin since its binding to the membrane stimulates the calcium …

Red blood cells (RBCs) are exposed to both external and internal sources of oxidants that
challenge their integrity and compromise their physiological function and supply of oxygen …

Background: Long-chain polyunsaturated fatty acids (PUFAs) are important modulators of
red blood cell (RBC) rheology. Dietary PUFAs are readily incorporated into the RBC …

Selenocysteine is a catalytic residue at the active site of all selenoenzymes in bacteria and
mammals, and it is incorporated into the polypeptide backbone by a co-translational process …