Cadherins play an important role in tissue homeostasis, as they are responsible for cell-cell
adhesion during embryogenesis, tissue morphogenesis, differentiation and carcinogenesis …

Epithelial-mesenchymal transition (EMT) refers to a process in which epithelial cells lose
apical-basal polarity and loosen cell–cell junctions to take on mesenchymal cell …

Background It is highly desirable to develop new therapeutic strategies for gastric cancer
given the low survival rate despite improvement in the past decades. Cadherin 17 (CDH17) …

LINC01857 has been proven to be involved in glioma and breast cancer. However, the
biological function of LINC01857 in diffuse large B-cell lymphoma (DLBCL) is poorly …

Cadherins mediate cell–cell adhesion through a dynamic process that is strongly dependent
on the cellular context and signaling. Cadherin regulation reflects the interplay between …

Background The cadherin-4 gene (CDH4), a member of the cadherin family genes, encodes
R-cadherin (R-cad); however, the function of this gene in different types of cancer remains …

Thyroid carcinoma is a common malignant tumor of endocrine system and head and neck.
Recurrence, metastasis and high malignant expression after routine treatment are serious …

In recent years, antibody-drug conjugate (ADC) technology, which uses monoclonal
antibodies (mAbs) to specifically deliver effective cytotoxic payloads to tumor cells, has …

Abstract Background Recurrence of Glioblastoma multiforme (GBM) seems to be the rule
despite combination therapies. Cell invasion and cell proliferation are major reasons for …

Abstract Background The decoction of Astragalus membranaceus (Huangqi) and Rhizoma
curcumae (Ezhu) has been reported as a potential antitumor agent for colorectal cancer …