B cell lymphoma (BCL) is a heterogeneous group of lymphoid malignancies which comprise
the majority of canine lymphomas. Diffuse large B cell lymphoma is the most common …

Human angiosarcoma and canine hemangiosarcoma reveal similarities not only in their
aggressive clinical behaviour, but especially in molecular landscape and genetic alterations …

Colorectal cancer (CRC) is recognized as the third most common malignancy and the
second most deadly in highly developed countries. Although the treatment of CRC has …

Recently, the incidence of hepatocellular carcinoma has increased worldwide. Cembranoid-
type diterpenes (CBDs) from tobacco exhibit good antimicrobial, antitumor, and …

Traditional medicines implicate consumption of plant crude extracts, which may consist of
extensive phytochemical diversity. Overall, the most biologically active extract of Peganum …

9 Gene Editing and Gene Therapy in Oncology Page 1 9 Gene Editing and Gene Therapy
in Oncology WESLEY A. WIERSON 1*, ALEX M. ABEL 1, ELIZABETH L. SIEGLER 2 …

Flavopiridol, a synthetic flavonoid derived from rohitukine, stands out as a powerful cyclin-
dependent kinase (CDK) inhibitor with significant anticancer properties. Its action …

Background/Aim: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a
potential anti-tumor agent. However, resistance to TRAIL has been reported in a number of …

Background/Aim: Triple-negative breast cancer (TNBC) can be characterized as the
deadliest breast cancer type considering the lack of efficacious therapeutics. Recombinant …

Due to their significant impact on human and animal health, cancer diseases are an area of
considerable concern for both human and veterinary medicine. Research on the cancer …