Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
developing pathogen‐specific memory that confers immunological protection. Memory and …

A fundamental prerequisite for the efficacy of cancer immunotherapy is the presence of
functional, antigen-specific T cells within the tumor. Neoantigen-directed therapy is a …

SARS-CoV-2 variants that escape neutralization and potentially affect vaccine efficacy have
emerged. T cell responses play a role in protection from reinfection and severe disease, but …

Major histocompatibility complex II (MHC II) molecules play a vital role in the onset and
control of cellular immunity. In a highly selective process, MHC II presents peptides derived …

Major histocompatibility complex class II (MHC‐II) molecules are expressed on the surface
of professional antigen‐presenting cells where they display peptides to T helper cells, which …

Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II
molecules would be valuable for vaccine development and cancer immunotherapies …

Abstract The Immune Epitope Database Analysis Resource (IEDB-AR, http://tools. iedb. org/)
is a companion website to the IEDB that provides computational tools focused on the …

We present an exceptional case of a patient with high-grade serous ovarian cancer, treated
with multiple chemotherapy regimens, who exhibited regression of some metastatic lesions …

Cancer vaccines must activate multiple immune cell types to be effective against aggressive
tumours. Here we report the impact of the structural presentation of two antigenic peptides …

COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …