The dengue virus NS1 protein; new roles in pathogenesis due to similarities with and affinity for the high-density lipoprotein (HDL)?

AC Alcalá, JE Ludert - PLoS Pathogens, 2023 - journals.plos.org
Dengue, the most important mosquito-borne viral disease transmitted to humans, is caused
by any of the 4 known serotypes of the dengue virus (DENV). Dengue is a systemic disease …

Sepsis–it is all about the platelets

D Cox - Frontiers in Immunology, 2023 - frontiersin.org
Sepsis is accompanied by thrombocytopenia and the severity of the thrombocytopenia is
associated with mortality. This thrombocytopenia is characteristic of disseminated …

Secretory pathways and multiple functions of nonstructural protein 1 in flavivirus infection

S Zhang, Y He, Z Wu, M Wang, R Jia, D Zhu… - Frontiers in …, 2023 - frontiersin.org
The genus Flavivirus contains a wide variety of viruses that cause severe disease in
humans, including dengue virus, yellow fever virus, Zika virus, West Nile virus, Japanese …

[HTML][HTML] Severe fever with thrombocytopenia syndrome virus replicates in platelets and enhances platelet activation

L Fang, S Yu, X Tian, W Fu, L Su, Z Chen, C Yan… - Journal of Thrombosis …, 2023 - Elsevier
Background Severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) infection
causes an emerging hemorrhagic fever in East Asia with a high mortality rate …

The role of macrophages-mediated communications among cell compositions of tumor microenvironment in cancer progression

M Li, P Jiang, S Wei, J Wang, C Li - Frontiers in Immunology, 2023 - frontiersin.org
Recent studies have revealed that tumor-associated macrophages are the most abundant
stromal cells in the tumor microenvironment and play an important role in tumor initiation …

[HTML][HTML] RETRACTED: severe fever with thrombocytopenia syndrome virus induces platelet activation and apoptosis via a reactive oxygen species-dependent …

YH Li, XH Wang, WW Huang, RR Tian, W Pang… - 2023 - Elsevier
The Journal carried out an investigation into this article after issues with Western (immuno-)
blots displayed in the article, and image duplication in a Figure (Figure 5) were highlighted …

Potential Pathways and Pathophysiological Implications of Viral Infection-Driven Activation of Kallikrein–Kinin System (KKS)

SVA Coelho, FM Augusto, LB Arruda - Viruses, 2024 - mdpi.com
Microcirculatory and coagulation disturbances commonly occur as pathological
manifestations of systemic viral infections. Research exploring the role of the kallikrein–kinin …

Thrombocytopenia in dengue infection: mechanisms and a potential application

AS Khazali, WH Hadrawi, F Ibrahim… - Expert Reviews in …, 2024 - cambridge.org
Thrombocytopenia is a common symptom and one of the warning signs of dengue virus
(DENV) infection. Platelet depletion is critical as it may lead to other severe dengue …

[HTML][HTML] Rotational thromboelastometry in critical phase of dengue infection: association with bleeding

W Wickramasinghe, BY Alvitigala, T Perera… - Research and Practice …, 2022 - Elsevier
Background The critical phase of dengue carries a high risk of bleeding. Associations of
coagulation test parameters and the risk of bleeding in the critical phase is unclear. This …

Increased plasma heparanase activity and endothelial glycocalyx degradation in dengue patients is associated with plasma leakage

B Buijsers, FM Garishah, SF Riswari… - Frontiers in …, 2021 - frontiersin.org
Background Endothelial hyper-permeability with plasma leakage and thrombocytopenia are
predominant features of severe dengue virus infection. It is well established that …