The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …

Type 2 immunity is orchestrated by a canonical group of cytokines primarily produced by
innate lymphoid cells, group 2, and their adaptive counterparts, CD4+ helper type 2 cells …

Mucus is a slimy hydrogel that lines the mucosal surfaces in our body, including the
intestines, stomach, eyes, lungs and urogenital tract. This glycoprotein-rich network is truly …

A characteristic feature of host responses to helminth infections is the development of
profound systemic and tissue-localised Type 2 immune responses that play critical roles in …

Innate lymphoid cells (ILCs) are critical mediators of immunological and physiological
responses at mucosal barrier sites. Whereas neurotransmitters can stimulate ILCs, the …

Contrary to first appearances, mucus structural biology is not an oxymoron. Though mucus
hydrogels derive their characteristics largely from intrinsically disordered, heavily …

Allergic immunity is orchestrated by group 2 innate lymphoid cells (ILC2s) and type 2 helper
T (Th2) cells prominently arrayed at epithelial-and microbial-rich barriers. However, ILC2s …

Although tuft cells were discovered over 60 years ago, their functions have long been
enigmatic, especially in human health. Nonetheless, tuft cells have recently emerged as key …

Group 2 innate lymphoid cells (ILC2s) are tissue-resident cells prominent at barrier sites.
Although precursors are found in blood, mature ILC2s can enter the circulation after small …