Type 2 diabetes mellitus (T2DM) is associated with increased total plasma free fatty acid
(FFA) concentrations and an elevated risk of cardiovascular disease. The exact mechanisms …

The glycosaminoglycans (GAGs) heparan sulfate, dermatan sulfate, and heparin are
important anticoagulants that inhibit clot formation through interactions with antithrombin and …

Zinc is an essential nutrient in the body; it is required for the catalytic activity of many
hundreds of human enzymes and virtually all biological processes, therefore its homeostasis …

Serum albumin–Co2+ interactions are of clinical importance. They play a role in mediating
the physiological effects associated with cobalt toxicity and are central to the albumin cobalt …

Mammalian histidine-rich glycoprotein (HRG) is a highly versatile and abundant blood
plasma glycoprotein with a diverse range of ligands that is involved in regulating many …

Decompensated liver cirrhosis has a dismal prognosis, with patients surviving on average
for 2–4 years after the first diagnosis of ascites. Albumin is an important tool in the therapy of …

Myocardial ischemia is difficult to diagnose effectively with still few well-defined biochemical
markers for identification in advance, or in the absence of myocardial necrosis.“Ischemia …

In mammalian blood plasma, serum albumin acts as a transport protein for free fatty acids,
other lipids and hydrophobic molecules including neurodegenerative peptides, and …

Serum albumin is a highly abundant plasma protein associated with the transport of metal
ions, pharmaceuticals, fatty acids and a variety of small molecules in the blood. Once …

The initiation, maintenance and regulation of blood coagulation is inexorably linked to the
actions of Zn2+ in blood plasma. Zn2+ interacts with a variety of haemostatic proteins in the …