The relationship between metabolism and cell cycle progression is complex and
bidirectional. Cells must rewire metabolism to meet changing biosynthetic demands across …

The human body is programmed with definite quantities, magnitudes, and proportions. At the
microscopic level, such definite sizes manifest in individual cells-different cell types are …

Cell cycle progression relies on coordinated changes in the composition and subcellular
localization of the proteome. By applying two distinct convolutional neural networks on …

Fluorescence microscopy has revolutionised biological research by enabling the
visualisation of subcellular structures at high resolution. With the increasing complexity and …

Cells vary in volume throughout their life cycle and in many other circumstances, while their
genome remains identical. Hence, the RNA production factory must adapt to changing …

Severe defects in cell size are a nearly universal feature of cancer cells. However, the
underlying causes are unknown. A previous study suggested that a hyperactive mutant of …

The highly conserved TOR signaling pathway is crucial for coordinating cellular growth with
the cell cycle machinery in eukaryotes. One of the two TOR complexes in budding yeast …

Environmental stress induces an arrest of the cell cycle. Thus, release from this arrest is
essential for cell survival. The cell-cycle-arrest occurs via the down regulation of the cyclins …

Growth-dependent accumulation of the limiting SBF transcription factor, composed of Swi4
and Swi6, occurs in G1 phase in budding yeast and is limiting for commitment to division …

Clonal cultures exhibit phenotypic variation in spite of being composed of genetically
identical cells under equal environmental conditions. Proliferation rate is one of the …