The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

Clinicians should have a low threshold to assess for objective evidence of GERD in IPF
patients. Antireflux surgery in IPF patients with GERD appears to improve lung function, but …

Rationale: It remains unclear how gastroesophageal reflux disease (GERD) affects allograft
microbial community composition in lung transplant recipients and its impact on lung …

Introduction Duodeno-gastroesophageal reflux aspiration is associated with chronic lung
allograft dysfunction (CLAD). Reflux aspirate can contain bile acids (BA), functional …

Background Antibody-mediated rejection (AMR) remains one of the major barriers for graft
survival after kidney transplantation. Our previous study suggested a gut microbiota …

Background Bronchiolitis obliterans syndrome (BOS) is the main limitation to long-term
survival following lung transplantation. Several studies generated promising results …

Background Lung transplant patients are at risk of developing chronic lung allograft
dysfunction (CLAD) of which bronchitis obliterans syndrome (BOS) is the most common …

BACKGROUND Aspiration is a relative contraindication to accepting donor lungs for
transplant and is currently assessed by visual inspection of the airways via bronchoscopy …

Background Gastroesophageal reflux disease (GERD) and aspiration of enteric contents are
associated with worse outcomes after lung transplantation. The purpose of this study was to …

The primary factor that limits long-term survival after lung transplantation is chronic lung
allograft dysfunction (CLAD). CLAD also impairs quality of life and increases the costs of …