Cellular model systems to study cardiovascular injury from chemotherapy
H Fonoudi, PW Burridge - Journal of thrombosis and thrombolysis, 2021 - Springer
In spite of all the efforts for generating efficient pharmacological treatment options for cancer
patients, the unwanted side effect of these substances on the cardiovascular system is …
patients, the unwanted side effect of these substances on the cardiovascular system is …
Opportunities and challenges for human microphysiological systems in drug development
SM Rahman, A Krishna, C Sullenberger… - ALTEX-Alternatives to …, 2024 - altex.org
Microphysiological systems (MPS) are complex in vitro tools that incorporate cells derived
from various healthy or disease-state human or animal tissues and organs. While MPS have …
from various healthy or disease-state human or animal tissues and organs. While MPS have …
[HTML][HTML] Independent compartmentalization of functional, metabolic, and transcriptional maturation of hiPSC-derived cardiomyocytes
KA Fetterman, M Blancard, DM Lyra-Leite, CG Vanoye… - Cell reports, 2024 - cell.com
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) recapitulate
numerous disease and drug response phenotypes, but cell immaturity may limit their …
numerous disease and drug response phenotypes, but cell immaturity may limit their …
Life cycle assessment of culture media with alternative compositions for cultured meat production
ME Wali, H Karinen, SB Rønning… - … International Journal of …, 2024 - Springer
Purpose Cultured meat is produced by cultivating animal cells in a bioreactor in a culture
medium that provides nutrients and growth factors. Among other animal sera, fetal bovine …
medium that provides nutrients and growth factors. Among other animal sera, fetal bovine …
Simultaneous Optical Imaging of Action Potentials and Calcium Transients in Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes
H Yang, Y Yang, Z Lu, JZ Zhang - Current Protocols, 2024 - Wiley Online Library
Cardiovascular diseases have emerged as one of the leading causes of human mortality,
but the discovery of new drugs has been hindered by the absence of suitable in vitro …
but the discovery of new drugs has been hindered by the absence of suitable in vitro …