Coronary atherosclerosis is the major cause of mortality and disability in developed nations.
A deeper understanding of mechanical properties of coronary arteries and hence their …

Aims Hypertension is accompanied by structural remodelling of vascular extracellular matrix
(ECM). Tissue inhibitor of metalloproteinases (TIMPs) inhibits matrix metalloproteinases …

Abstract Models of vascular mechanics are necessary to predict the response of an artery
under a variety of loads, for complex geometries, and in pathological adaptation. Classic …

The microstructural deformation-mechanical loading relation of the blood vessel wall is
essential for understanding the overall mechanical behavior of vascular tissue in health and …

The mechanical response of arteries under physiological loads can be delineated into
passive and active components. The passive response is governed by the load-bearing …

Although vascular smooth muscle cells (VSMCs) are pivotal in physiology and pathology,
there is a lack of detailed morphological data on these cells. The objective of this study was …

Currently, there is no full three-dimensional (3D) microstructural mechanical model of
coronary artery based on measured microstructure including elastin, collagen and smooth …

Triaxial active and passive mechanical properties of coronary arteries are needed for
understanding arterial mechanics in health and disease. The aim of the study was to …

The elastic abdominal aorta and muscular femoral artery are susceptible to aneurysm and
atherosclerosis, respectively. The vessel wall mechanics should be an important element for …

Since vascular tone is regulated by smooth muscle cells in the media layer, a multilayer
mechanical model is required for blood vessels. Here, we performed biaxial mechanical …