Collagen provides mechanical and biological support for virtually all human tissues in the
extracellular matrix (ECM). Its defining molecular structure, the triple-helix, could be …

Human tissue consists of various tissue-specific cells, extracellular matrix components and
microstructures, and growth factors. With promising multi-cell and multi-material integration …

Efficient strategies to promote microvascularization in vascular tissue engineering, a central
priority in regenerative medicine, are still scarce; nano-and micro-sized aggregates and …

In the field of regenerative medicine, the importance of 3D bioprinting is self-evident and
nonnegligible. However, 3D bioprinting technology also requires bioink with excellent …

The integration of tumor-on-a-chip technology with mini-tissues or organoids has emerged
as a powerful approach in cancer research and drug development. This review provides an …

The rising prevalence of bone injuries has increased the demand for minimally invasive
treatments. Microbead hydrogels, renowned for cell encapsulation, provide a versatile …

Cell patterning technology is an effective technique to understand cell behaviors by
precisely controlling the position of cells revealing the major contributions of cells in basic …

Background Joint degeneration and large or complex bone defects are a significant source
of morbidity and diminished quality of life worldwide. There is an unmet need for a functional …

Micro/nanomaterial-based drug and cell delivery systems play an important role in
biomedical fields for their injectability and targeting. Microfluidics is a rapidly developing …

The specific spatial distribution of tissue generates a heterogeneous micromechanical
environment that provides ideal conditions for diverse functions such as regeneration and …