The mesenchymal stem cell secretome: A new paradigm towards cell-free therapeutic mode in regenerative medicine

P Kumar, S Kandoi, R Misra, S Vijayalakshmi… - Cytokine & growth factor …, 2019 - Elsevier
Abstract Mesenchymal Stem Cells (MSCs) have been shown to be a promising candidate for
cell-based therapy. The therapeutic potential of MSCs, towards tissue repair and wound …

[HTML][HTML] Cell–scaffold interactions in tissue engineering for oral and craniofacial reconstruction

F Wang, X Cai, Y Shen, L Meng - Bioactive Materials, 2023 - Elsevier
Tissue engineering (TE) is critical in oral and craniofacial reconstruction. One of the most
popular topics on the biomaterial-based tissue regeneration process may be the interaction …

Silk fibroin and sericin differentially potentiate the paracrine and regenerative functions of stem cells through multiomics analysis

Y Zhang, R Sheng, J Chen, H Wang, Y Zhu… - Advanced …, 2023 - Wiley Online Library
Silk fibroin (SF) and sericin (SS), the two major proteins of silk, are attractive biomaterials
with great potential in tissue engineering and regenerative medicine. However, their …

Emergence of the stem cell secretome in regenerative engineering

L Daneshmandi, S Shah, T Jafari, M Bhattacharjee… - Trends in …, 2020 - cell.com
The secretome is defined as the set of molecules and biological factors that are secreted by
cells into the extracellular space. In the past decade, secretome-based therapies have …

Exosomes from conditioned media of bone marrow-derived mesenchymal stem cells promote bone regeneration by enhancing angiogenesis

R Takeuchi, W Katagiri, S Endo, T Kobayashi - PLoS One, 2019 - journals.plos.org
Growth factors in serum-free conditioned media from human bone marrow-derived
mesenchymal stem cells (MSC-CM) are known to be effective in bone regeneration …

The regulatory role of micro RNA s in angiogenesis‐related diseases

LL Sun, WD Li, FR Lei, XQ Li - Journal Of Cellular And …, 2018 - Wiley Online Library
Micro RNA s (mi RNA s) are small non‐coding RNA s that regulate gene expression at a
post‐transcriptional level via either the degradation or translational repression of a target …

[HTML][HTML] Osteogenesis, angiogenesis and immune response of Mg-Al layered double hydroxide coating on pure Mg

S Cheng, D Zhang, M Li, X Liu, Y Zhang, S Qian… - Bioactive materials, 2021 - Elsevier
Layered double hydroxides (LDHs) are widely studied to enhance corrosion resistance and
biocompatibility of Mg alloys, which are promising bone implants. However, the influence of …

Oral bone tissue regeneration: mesenchymal stem cells, secretome, and biomaterials

A Gugliandolo, L Fonticoli, O Trubiani… - International journal of …, 2021 - mdpi.com
In the last few decades, tissue engineering has become one of the most studied medical
fields. Even if bone shows self-remodeling properties, in some cases, due to injuries or …

Mesenchymal stromal cell-based bone regeneration therapies: from cell transplantation and tissue engineering to therapeutic secretomes and extracellular vesicles

D Marolt Presen, A Traweger, M Gimona… - … in bioengineering and …, 2019 - frontiersin.org
Effective regeneration of bone defects often presents significant challenges, particularly in
patients with decreased tissue regeneration capacity due to extensive trauma, disease …

Advances in mesenchymal stem cell conditioned medium-mediated periodontal tissue regeneration

H Lin, H Chen, X Zhao, Z Chen, P Zhang, Y Tian… - Journal of translational …, 2021 - Springer
Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and
hard periodontal tissues. Complete periodontal regeneration in clinics using the currently …