Gastroretentive technologies in tandem with controlled-release strategies: A potent answer to oral drug bioavailability and patient compliance implications

NN Vrettos, CJ Roberts, Z Zhu - Pharmaceutics, 2021 - mdpi.com
There have been many efforts to improve oral drug bioavailability and therapeutic efficacy
and patient compliance. A variety of controlled-release oral delivery systems have been …

Highlighting the impact of chitosan on the development of gastroretentive drug delivery systems

MPC de Souza, RM Sábio, T de Cassia Ribeiro… - International Journal of …, 2020 - Elsevier
The development of gastroretentive systems have been growing lately due to the high
demand for carriers that increase drug bioavailability and therapeutic effectiveness after oral …

Thallium and selenite doped carbonated hydroxyapatite: microstructural features and anticancer activity assessment against human lung carcinoma

K Shoueir, MK Ahmed, SAA Gaber, M El-Kemary - Ceramics International, 2020 - Elsevier
Background The fabrication of nanostructure local delivery system from a biocompatible
biomaterial is highly requested for biomedical applications. The therapeutic use of thallium …

Sodium alginate-based smart gastro-retentive drug delivery system of revaprazan loaded SLNs; Formulation and characterization

HN Raja, F ud Din, K Shabbir, S Khan… - International Journal of …, 2023 - Elsevier
Revaprazan (REV), a novel reversible Proton Pump Inhibitor (PPI) used to treat peptic
ulcers, faces challenges in therapeutic efficacy due to its poor dissolution properties and a …

In-depth study into polymeric materials in low-density gastroretentive formulations

N Iglesias, E Galbis, L Romero-Azogil, E Benito… - Pharmaceutics, 2020 - mdpi.com
The extensive use of oral dosage forms for the treatment of diseases may be linked to
deficient pharmacokinetic properties. In some cases the drug is barely soluble; in others, the …

Merging konjac glucomannan with other copolymeric hydrogels as a cutting-edge liquid raft system for dual delivery of etoricoxib and famotidine

NA Shoman, M Saady, M Teaima, R Abdelmonem… - Drug Delivery, 2023 - Taylor & Francis
This study aimed to formulate and evaluate a floating raft system for the co-delivery of
etoricoxib (ETO) and famotidine (FAM) using a combination of glucomannan with …

[HTML][HTML] Recent advances in alginate based gastroretentive technologies for drug delivery applications

O Sen, S Manna, G Nandi, S Jana, S Jana - Medicine in Novel Technology …, 2023 - Elsevier
The efficacy of orally delivered medicines can be maximized through enhancing the gastric
residence period and modifying the drug release pattern according to therapeutic need …

Raft-forming gastro-retentive formulations based on Centella asiatica extract-solid dispersions for gastric ulcer treatment

S Wannasarit, S Mahattanadul, O Issarachot… - European Journal of …, 2020 - Elsevier
Liquid raft-forming formulations comprising solid dispersions of glycoside-rich Centella
asiatica extract and Eudragit® EPO (GR-SD) were developed to achieve prolonged delivery …

[PDF][PDF] Flow injection analysis with turbidity detection for the quantitative determination of mebeverine hydrochloride in pharmaceutical formulations

NS Turkey, JN Jeber - Baghdad Science Journal, 2022 - iasj.net
The main objective of this paper is to develop and validate flow injection method, a precise,
accurate, simple, economic, low cost and specific turbidimetric method for the quantitative …

Sulpiride gastro-retentive floating microsponges; analytical study, in vitro optimization and in vivo characterization

MA Younis, MR El-Zahry, MA Tallat… - Journal of drug …, 2020 - Taylor & Francis
Abstract Sulpiride (SUL), anti-dopaminergic drug, has a specific site for absorption located in
the upper portion of the gastrointestinal tract hence, its oral delivery represents a challenge …