A journey from structure to function of bacterial lipopolysaccharides

F Di Lorenzo, KA Duda, R Lanzetta, A Silipo… - Chemical …, 2021 - ACS Publications
Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

Function and biogenesis of lipopolysaccharides

B Bertani, N Ruiz - Ecosal plus, 2018 - Am Soc Microbiol
The cell envelope is the first line of defense between a bacterium and the world-at-large.
Often, the initial steps that determine the outcome of chemical warfare, bacteriophage …

Bacterial cell mechanics

GK Auer, DB Weibel - Biochemistry, 2017 - ACS Publications
Cellular mechanical properties play an integral role in bacterial survival and adaptation.
Historically, the bacterial cell wall and, in particular, the layer of polymeric material called the …

Lipopolysaccharide endotoxins

CRH Raetz, C Whitfield - Annual review of biochemistry, 2002 - annualreviews.org
▪ Abstract Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain
known as lipid A (or endotoxin), a nonrepeating “core” oligosaccharide, and a distal …

Molecular basis of bacterial outer membrane permeability revisited

H Nikaido - Microbiology and molecular biology reviews, 2003 - Am Soc Microbiol
Gram-negative bacteria characteristically are surrounded by an additional membrane layer,
the outer membrane. Although outer membrane components often play important roles in …

The Antimicrobial Mechanism of Action of Epsilon-Poly-l-Lysine

M Hyldgaard, T Mygind, BS Vad… - Applied and …, 2014 - Am Soc Microbiol
ABSTRACT Epsilon-poly-l-lysine (ε-PL) is a natural antimicrobial cationic peptide which is
generally regarded as safe (GRAS) as a food preservative. Although its antimicrobial activity …

The Role of Outer Membrane Proteins and Lipopolysaccharides for the Sensitivity of Escherichia coli to Antimicrobial Peptides

A Ebbensgaard, H Mordhorst, FM Aarestrup… - Frontiers in …, 2018 - frontiersin.org
Bacterial resistance to classical antibiotics is emerging worldwide. The number of infections
caused by multidrug resistant bacteria is increasing and becoming a serious threat for …

Efflux-mediated drug resistance in bacteria

XZ Li, H Nikaido - Drugs, 2004 - Springer
Drug resistance in bacteria, and especially resistance to multiple antibacterials, has
attracted much attention in recent years. In addition to the well known mechanisms, such as …

Structure of bacterial lipopolysaccharides

M Caroff, D Karibian - Carbohydrate research, 2003 - Elsevier
Bacterial lipopolysaccharides are the major components of the outer surface of Gram-
negative bacteria They are often of interest in medicine for their immunomodulatory …

Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica

DE Heinrichs, JA Yethon, C Whitfield - Molecular microbiology, 1998 - Wiley Online Library
Bacterial lipopolysaccharides (LPS) are unique and complex glycolipids that provide
characteristic components of the outer membranes of Gram‐negative bacteria. In LPS of the …