Statins are a class of drugs widely used worldwide to manage hypercholesterolemia and the
prevention of secondary heart attacks. Currently, available statins vary in terms of their …

Simple Summary Retrospective studies of common malignancies such as head and neck
cancer often report lower incidence and/or better outcomes for patients incidentally treated …

Cholesterol, an essential molecule for cell structure, function, and viability, plays crucial
roles in the development, progression, and survival of cancer cells. Earlier studies have …

According to clinical studies, statins improve the efficacy of programmed death-
1/programmed death-ligand 1 (PD-1/PD-L1) blockade therapy for breast cancer; however …

Statins are cholesterol-lowering agents that act as inhibitors of 3-hydroxy-3-methyl-glutaryl-
coenzymeA (HMG CoA) reductase. Recently, statins have received a lot of attention …

The development of immune checkpoint blockade (ICB) therapies has been instrumental in
advancing the field of immunotherapy. Despite the prominence of these treatments, many …

Cancer immunotherapy, including the inhibition of immune checkpoints, improves the tumor
immune microenvironment and is an effective tool for cancer therapy. More effective and …

Lung cancer is a common neoplasm, usually treated through chemotherapy, radiotherapy
and/or surgery. Both clinical and experimental studies on cancer cells suggest that some …

Simple Summary Since the approval of immune checkpoint inhibitors for solid tumors,
concerns have been raised about the role of the microbiota on immunotherapy success and …

Immune checkpoint inhibitors (ICIs) exhibit remarkable antitumor activity and immune-
related cardiotoxicity of unknown pathomechanism. The aim of the study was to investigate …