Integrated metabolomic–genomic workflows accelerate microbial natural product discovery
The pairing of analytical chemistry with genomic techniques represents a new wave in
natural product chemistry. With an increase in the availability of sequencing and assembly of …
natural product chemistry. With an increase in the availability of sequencing and assembly of …
Beyond the approved: target sites and inhibitors of bacterial RNA polymerase from bacteria and fungi
Covering: 2016 to 2022 RNA polymerase (RNAP) is the central enzyme in bacterial gene
expression representing an attractive and validated target for antibiotics. Two well-known …
expression representing an attractive and validated target for antibiotics. Two well-known …
Correlative metabologenomics of 110 fungi reveals metabolite–gene cluster pairs
Natural products research increasingly applies-omics technologies to guide molecular
discovery. While the combined analysis of genomic and metabolomic datasets has proved …
discovery. While the combined analysis of genomic and metabolomic datasets has proved …
Streptomyces learnhanii sp. nov., unveiling a Mangrove-Derived Novel “Modern Actinobacteria” in Malaysia
JWF Law, V Letchumanan… - … In Microbes & …, 2023 - journals.hh-publisher.com
Streptomyces learnhanii sp. nov. MUM 203J T was isolated from Malaysia mangrove soil.
This Gram-positive bacterium produces pale greenish-yellow aerial and greyish-yellow …
This Gram-positive bacterium produces pale greenish-yellow aerial and greyish-yellow …
Biosynthetic gene cluster profiling from North Java Sea Virgibacillus salarius reveals hidden potential metabolites
Abstract Virgibacillus salarius 19. PP. SC1. 6 is a coral symbiont isolated from Indonesia's
North Java Sea; it has the ability to produce secondary metabolites that provide survival …
North Java Sea; it has the ability to produce secondary metabolites that provide survival …
[HTML][HTML] Synthetic biology in Indonesia: Potential and projection in a country with mega biodiversity
Synthetic biology has gained many interest around the globe in the last two decades, not
only due to its rapid development but also the potential to provide addressable solutions …
only due to its rapid development but also the potential to provide addressable solutions …
Genome features and secondary metabolite potential of the marine symbiont Streptomyces sp. RS2
Streptomyces sp. RS2 was isolated from an unidentified sponge collected around Randayan
Island, Indonesia. The genome of Streptomyces sp. RS2 consists of a linear chromosome of …
Island, Indonesia. The genome of Streptomyces sp. RS2 consists of a linear chromosome of …
ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria
MA Feeney, JT Newitt, E Addington… - Microbial …, 2022 - microbiologyresearch.org
Actinobacteria is an ancient phylum of Gram-positive bacteria with a characteristic high GC
content to their DNA. The ActinoBase Wiki is focused on the filamentous actinobacteria, such …
content to their DNA. The ActinoBase Wiki is focused on the filamentous actinobacteria, such …
Untargeted Metabolomics of Streptomyces Species Isolated from Soils of Nepal
Actinomycetes are natural architects of numerous secondary metabolites including
antibiotics. With increased multidrug-resistant (MDR) pathogens, antibiotics that can combat …
antibiotics. With increased multidrug-resistant (MDR) pathogens, antibiotics that can combat …
High Plasticity of the Amicetin Biosynthetic Pathway in Streptomyces sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and …
N Aryal, J Chen, K Bhattarai, O Hennrich… - Journal of Natural …, 2022 - ACS Publications
A chemical reinvestigation of the Indonesian strain Streptomyces sp. SHP 22-7 led to the
isolation of three new pyrimidine nucleosides, along with six known analogues and …
isolation of three new pyrimidine nucleosides, along with six known analogues and …