Penetrance estimate of LRRK2 p.G2019S mutation in individuals of non‐Ashkenazi Jewish ancestry
AJ Lee, Y Wang, RN Alcalay… - Movement …, 2017 - Wiley Online Library
Background Penetrance estimates of the leucine‐rich repeat kinase 2 (LRRK2) p. G2019S
mutation for PD vary widely (24%‐100%). The p. G2019S penetrance in individuals of …
mutation for PD vary widely (24%‐100%). The p. G2019S penetrance in individuals of …
Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease
Objective To compute penetrance and recurrence risk using a genome‐wide PRS (including
and excluding the APOE region) in families with Alzheimer's disease. Methods Genotypes …
and excluding the APOE region) in families with Alzheimer's disease. Methods Genotypes …
Connectivity of corticostriatal circuits in nonmanifesting LRRK2 G2385R and R1628P carriers
D Zhang, J Yao, J Ma, L Gao, J Sun… - CNS Neuroscience …, 2022 - Wiley Online Library
Background Neuroimaging studies have shown that the functional connectivity (FC) of
corticostriatal circuits in nonmanifesting leucine‐rich repeat kinase 2 (LRRK2) G2019S …
corticostriatal circuits in nonmanifesting leucine‐rich repeat kinase 2 (LRRK2) G2019S …
[图书][B] Statistical Methods for Genetic Studies with Family History of Diseases
AJ Lee - 2019 - search.proquest.com
The theme of this dissertation is to develop statistical methods for genetic studies with family
history of diseases. Family history of disease is a major risk factor for many health outcomes …
history of diseases. Family history of disease is a major risk factor for many health outcomes …