[PDF][PDF] Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling

ZR Craig, W Wang, JA Flaws - Reproduction, 2011 - researchgate.net
Endocrine-disrupting chemicals (EDCs) are exogenous agents with the ability to interfere
with processes regulated by endogenous hormones. One such process is female …

Toxic effects and molecular mechanism of doxorubicin on different organs–an update

K Renu, LP Pureti, B Vellingiri… - Toxin …, 2022 - Taylor & Francis
Doxorubicin is an extensively used anti-neoplastic drug used for solid and hematogenous
cancer since the 1950s, and its usage is limited due to its toxic effects upon various organs …

Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicity

P Bhattacharya, AF Keating - Toxicology and applied pharmacology, 2012 - Elsevier
The mammalian ovary is a heterogeneous organ and contains oocyte-containing follicles at
varying stages of development. The most immature follicular stage, the primordial follicle …

Inhibition of human and rat testicular steroidogenic enzyme activities by bisphenol A

L Ye, B Zhao, G Hu, Y Chu, RS Ge - Toxicology letters, 2011 - Elsevier
Bisphenol A (BPA) is a potential endocrine disruptor. It has been shown that it reduces
serum testosterone level in rodents after exposure. However, the mechanism is unclear. The …

Effect of environmental contaminants on mammalian testis

F PT Manfo, EA Nantia… - Current molecular …, 2014 - ingentaconnect.com
Exposure of humans and wildlife to pollutants released in the environment is a centre of
attention nowadays. Many of these chemicals (generally referred to as environmental …

Effect of doxorubicin-induced ovarian toxicity on mouse ovarian granulosa cells

T Zhang, WH He, LL Feng, HG Huang - Regulatory toxicology and …, 2017 - Elsevier
The objective of this study was to identify the effect of doxorubicin-induced ovarian toxicity
on mouse ovarian granulosa cells. After granulosa cells were treated with doxorubicin at the …

A novel action of endocrine-disrupting chemicals on wildlife; DDT and its derivatives have remained in the environment

A Matsushima - International journal of molecular sciences, 2018 - mdpi.com
Huge numbers of chemicals are released uncontrolled into the environment and some of
these chemicals induce unwanted biological effects, both on wildlife and humans. One class …

Methoxychlor reduces estradiol levels by altering steroidogenesis and metabolism in mouse antral follicles in vitro

MS Basavarajappa, ZR Craig… - Toxicology and applied …, 2011 - Elsevier
The organochlorine pesticide methoxychlor (MXC) is a known endocrine disruptor that
affects adult rodent females by causing reduced fertility, persistent estrus, and ovarian …

[PDF][PDF] Impact of endocrine disruptors on ovarian steroidogenesis

A Mlynarcikova, M Fickova, S Scsukova - Endocr Regul, 2014 - researchgate.net
Production of steroid hormones by the ovary plays a key role in the female phenotype
maintenance, as well as is critical for regular ovarian processes, including follicle growth …

The ameliorative effect of propolis against methoxychlor induced ovarian toxicity in rat

EE El-Sharkawy, AOG Kames, SM Sayed… - Experimental and …, 2014 - Elsevier
A study was designed to evaluate ameliorative effect of propolis against methoxychlor
(MXC) induced ovarian toxicity in rat. The organochlorine pesticide (MXC) is a known …