Recent advances of chroman-4-one derivatives: synthetic approaches and bioactivities

S Emami, Z Ghanbarimasir - European Journal of Medicinal Chemistry, 2015 - Elsevier
Chroman-4-one scaffold is a privileged structure in heterocyclic chemistry and drug
discovery. Also, chroman-4-ones are important intermediates and interesting building blocks …

Oxime‐Derived Iminyl Radicals in Selective Processes of Hydrogen Atom Transfer and Addition to Carbon‐Carbon π‐Bonds

IB Krylov, OO Segida, AS Budnikov… - … Synthesis & Catalysis, 2021 - Wiley Online Library
Oximes represent one of the fundamental organic compound classes with a wide range of
synthetic applications. In the last decade O‐substituted oximes were recognized as the …

[HTML][HTML] Pentylenetetrazole-induced kindling mouse model

T Shimada, K Yamagata - Journal of visualized experiments: JoVE, 2018 - ncbi.nlm.nih.gov
Pentylenetetrazole (PTZ) is a GABA-A receptor antagonist. An intraperitoneal injection of
PTZ into an animal induces an acute, severe seizure at a high dose, whereas sequential …

Chromanone-A prerogative therapeutic scaffold: an overview

S Kamboj, R Singh - Arabian journal for science and engineering, 2022 - Springer
Chromanone or Chroman-4-one is the most important and interesting heterobicyclic
compound and acts as a building block in medicinal chemistry for isolation, designing and …

Design, synthesis, in vivo and in silico evaluation of phenacyl triazole hydrazones as new anticonvulsant agents

L Dehestani, N Ahangar, SM Hashemi, H Irannejad… - Bioorganic …, 2018 - Elsevier
A series of phenacyl triazole hydrazones 3 have been designed based on the hybridization
of (arylalkly) triazole and aroyl hydrazone scaffolds as new anticonvulsant agents. The target …

A review of biologically active oxime ethers

T Kosmalski, D Kupczyk, S Baumgart, R Paprocka… - Molecules, 2023 - mdpi.com
Oxime ethers are a class of compounds containing the> C= NOR moiety. The presence of
this moiety affects the biological activity of the compounds. In this review, the structures of …

Oxime ethers as versatile precursors in organic synthesis: a review

Z Mirjafary, M Abdoli, H Saeidian, S Boroon… - RSC …, 2015 - pubs.rsc.org
Oxime ethers as versatile precursors in organic synthesis: a review - RSC Advances (RSC
Publishing) DOI:10.1039/C5RA15299B Royal Society of Chemistry View PDF VersionPrevious …

Electrochemical Synthesis of O‐Phthalimide Oximes from α‐Azido Styrenes via Radical Sequence: Generation, Addition and Recombination of Imide‐N‐Oxyl and …

SA Paveliev, AI Churakov… - Advanced Synthesis …, 2020 - Wiley Online Library
Electrochemically induced radical‐initiated reaction of vinyl azides with N‐
hydroxyphthalimide resulting O‐phthalimide oximes with challenging for organic chemistry …

Synthesis of 2-aryl-3-triazolyl-indoles from phenacyltriazole-derived hydrazones: Exploring new scaffolds for anticonvulsant activity

SM Hashemi, S Emami, PH Masihi, A Shakiba… - Journal of Molecular …, 2023 - Elsevier
Abstract A novel series of 1-(2-(halophenyl)-2-(2-arylhydrazono) ethyl)-1H-1, 2, 4-triazoles
7a-l and their Fischer indolic products namely 2-(halophenyl)-3-(1H-1, 2, 4-triazol-1-yl)-1H …

Imidazole as an anti-epileptic: an overview

R Mishra, S Ganguly - Medicinal Chemistry Research, 2012 - Springer
Imidazole is incorporated into many important biological molecules. The major revolution in
the field of imidazole derivatives with antiepileptic properties came with the synthesis of …