[HTML][HTML] GSK-3β: An exuberating neuroinflammatory mediator in Parkinson's disease

SS Khan, S Janrao, S Srivastava, SB Singh… - Biochemical …, 2023 - Elsevier
Neuroinflammation is a critical degradative condition affecting neurons in the brain.
Progressive neurodegenerative conditions such as Alzheimer's disease and Parkinson's …

Integration of miRNA's theranostic potential with nanotechnology: promises and challenges for Parkinson's disease therapeutics

KP Tryphena, G Singh, N Jain, P Famta… - Mechanisms of Ageing …, 2023 - Elsevier
Despite the wide research going on in Parkinson's disease (PD), the burden of PD still
remains high and continues to increase. The current drugs available for the treatment of PD …

Involvement of miRNA on epigenetics landscape of Parkinson's disease: From pathogenesis to therapeutics

SN Uppala, KP Tryphena, P Naren, S Srivastava… - Mechanisms of Ageing …, 2023 - Elsevier
The development of novel therapeutics for the effective management of Parkinson's disease
(PD) is undertaken seriously by the scientific community as the burden of PD continues to …

Paraquat and Parkinson's disease: The molecular crosstalk of upstream signal transduction pathways leading to apoptosis

WZ Chung See, R Naidu… - Current …, 2024 - ingentaconnect.com
Parkinson's disease (PD) is a heterogeneous disease involving a complex interaction
between genes and the environment that affects various cellular pathways and neural …

[HTML][HTML] Neuroprotective effects of hesperetin on H2O2-induced damage in neuroblastoma SH-SY5Y cells

HR Moon, JM Yun - Nutrition Research and Practice, 2023 - ncbi.nlm.nih.gov
RESULTS Subsequent experiments utilized various non-toxic hesperetin concentrations,
establishing that hesperetin notably decreased intracellular ROS and NO production in H 2 …

Effects of apples (Malus domestica) and their derivatives on metabolic conditions related to inflammation and oxidative stress and an overview of by-products use in …

OS Girotto, OO Furlan, RC Moretti Junior… - Critical Reviews in …, 2024 - Taylor & Francis
Apple (Malus domestica) is the third most produced fruit worldwide. It is a well-known source
of bioactive compounds mainly represented by hydroxycinnamic acids, flavan-3-ols …

The Neuroprotective Effects of Agmatine on Parkinson's Disease: Focus on Oxidative Stress, Inflammation and Molecular Mechanisms

MY Zamanian, M Nazifi, LG Khachatryan, N Taheri… - Inflammation, 2024 - Springer
Agmatine (AGM), a naturally occurring polyamine derived from L-arginine, has shown
significant potential for neuroprotection in Parkinson's Disease (PD) due to its multifaceted …

Investigating affective neuropsychiatric symptoms in rodent models of Parkinson's disease

L Boi, G Fisone - International Review of Neurobiology, 2024 - Elsevier
Affective neuropsychiatric disorders such as depression, anxiety and apathy are among the
most frequent non-motor symptoms observed in people with Parkinson's disease (PD) …

[HTML][HTML] The alleviative effect of Calendula officinalis L. extract against Parkinson's disease-like pathology in zebrafish via the involvement of autophagy activation

M Wang, H Ye, P Jiang, J Liu, B Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder. However, effective preventative or therapeutic agents for PD remain largely limited …

Methamphetamine and REM sleep deprivation interact to affect behavioral performance in adult and adolescent rats

A Brimvandi, SE Nedaei, A Pourmotaabed, K Sahveisi… - Brain Research, 2024 - Elsevier
Drug addiction may result in sleep problems. Importantly, sleep deprivation (SD) is known as
an important risk factor for relapse to drug abuse as SD mimics the effects of …