Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

FAK in cancer: from mechanisms to therapeutic strategies

HH Chuang, YY Zhen, YC Tsai, CH Chuang… - International journal of …, 2022 - mdpi.com
Focal adhesion kinase (FAK), a non-receptor tyrosine kinase, is overexpressed and
activated in many cancer types. FAK regulates diverse cellular processes, including growth …

Eukaryotic cell size regulation and its implications for cellular function and dysfunction

Y Chadha, A Khurana… - Physiological …, 2024 - journals.physiology.org
Depending on cell type, environmental inputs, and disease, the cells in the human body can
have widely different sizes. In recent years, it has become clear that cell size is a major …

YAP‐TEAD mediates PPAR α–induced hepatomegaly and liver regeneration in mice

S Fan, Y Gao, A Qu, Y Jiang, H Li, G Xie, X Yao… - …, 2022 - Wiley Online Library
Abstract Background and Aims Peroxisome proliferator–activated receptor α (PPARα,
NR1C1) is a ligand‐activated nuclear receptor involved in the regulation of lipid catabolism …

[HTML][HTML] Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK

C Tan, MB Ginzberg, R Webster, S Iyengar, S Liu… - Developmental Cell, 2021 - cell.com
While molecules that promote the growth of animal cells have been identified, it remains
unclear how such signals are orchestrated to determine a characteristic target size for …

Resveratrol inhibits proliferation and induces apoptosis via the Hippo/YAP pathway in human colon cancer cells

X Qin, H Luo, Y Deng, X Yao, J Zhang, B He - Biochemical and Biophysical …, 2022 - Elsevier
High malignancy and mortality in colon cancer require clarifying the underlying mechanisms
of colon cancer carcinogenesis and exploring new targets or drugs for the clinical treatment …

What programs the size of animal cells?

S Liu, C Tan, M Tyers, A Zetterberg… - Frontiers in Cell and …, 2022 - frontiersin.org
The human body is programmed with definite quantities, magnitudes, and proportions. At the
microscopic level, such definite sizes manifest in individual cells-different cell types are …

Macroscopic quorum sensing sustains differentiating embryonic stem cells

H Daneshpour, P Van den Bersselaar… - Nature chemical …, 2023 - nature.com
Cells can secrete molecules that help each other's replication. In cell cultures, chemical
signals might diffuse only within a cell colony or between colonies. A chemical signal's …

Lipophilic statins inhibit YAP coactivator transcriptional activity in HCC cells through Rho-mediated modulation of actin cytoskeleton

JN Benhammou, B Qiao, A Ko… - American Journal …, 2023 - journals.physiology.org
Hepatocellular carcinoma (HCC) is the third leading cause of liver-related death. Lipophilic
statins have been associated with a decrease in HCC incidence, raising the possibility of …

Hippo pathway in cell–cell communication: emerging roles in development and regeneration

A Nita, T Moroishi - Inflammation and Regeneration, 2024 - Springer
The Hippo pathway is a central regulator of tissue growth that has been widely studied in
mammalian organ development, regeneration, and cancer biology. Although previous …