CREB is a transcription factor that regulates diverse cellular responses, including
proliferation, survival, and differentiation. CREB is induced by a variety of growth factors and …

The cyclic AMP response element binding (CREB) protein has pleiotropic activities in
physiologic processes. Due to its central position downstream of many growth signaling …

The human immunodeficiency virus type I (HIV-1) has developed several strategies to
condition the host environment to promote viral replication and spread. Viral proteins have …

Physical damage to the peripheral nerves triggers Schwann cell injury response in the distal
nerves in an event termed Wallerian degeneration: the Schwann cells degrade their myelin …

Autophagy is a homeostatic mechanism of lysosomal degradation. Defective autophagy has
been linked to various disorders such as impaired control of pathogens and …

Understanding how hepatitis C virus (HCV) induces and circumvents the host's natural killer
(NK) cell-mediated immunity is of critical importance in efforts to design effective …

Mushrooms are a highly valuable source of substances that possess unique biological
properties and medicinal efficacy. Medicinal mushrooms traditionally have been used to …

In response to infection by fungal pathogens, the innate immune system recognises specific
fungal pathogen associated molecular patterns (PAMPs) via pattern recognition receptors …

Infection with dengue virus (DENV) causes both mild dengue fever and severe dengue
diseases, such as dengue hemorrhagic fever and dengue shock syndrome. The pathogenic …

We recently reported that the human immunodeficiency virus type-1 (HIV-1) Tat protein
induced the expression of programmed death ligand-1 (PD-L1) on dendritic cells (DCs) …