The regenerative capacity of bone is indispensable for growth, given that accidental injury is
almost inevitable. Bone regenerative capacity is relevant for the aging population globally …

Piezoelectric effect produces an electrical signal when stress is applied to the bone. When
the integrity of the bone is destroyed, the biopotential within the defect site is reduced and …

The cross-talk between stem cells and their microenvironment has been shown to have a
direct impact on stem cells' decisions about proliferation, growth, migration, and …

In this article, we provide an extensive review of the recent literature of the signaling
pathways modulated by Pulsed Electromagnetic Fields (PEMFs) and PEMFs clinical …

The residual bone tumor and defects which is caused by surgical therapy of bone tumor is a
major and important problem in clinicals. And the sequential treatment for irradiating …

Mesenchymal stem cells (MSCs) are the main cell players in tissue repair and thanks to their
self-renewal and multi-lineage differentiation capabilities, they gained significant attention …

Electrical stimulation has shown to be a promising approach for promoting osseointegration
in bone anchoring implants, where osseointegration defines the biological bonding between …

Non‑traumatic osteonecrosis of the femoral head is the main cause of disability in young
individuals and incurs major health care expenditure. The lifestyle changes in recent years …

Environmental biophysical interactions are recognized to play an essential part in the
human biological processes associated with trauma recovery. Many studies over several …

The US FDA has approved pulsed electromagnetic fields (PEMFs) as a safe and effective
treatment for nonunions of bone. Despite its clinical use, the mechanisms of action of …