Obesity-induced neuroinflammation: beyond the hypothalamus

O Guillemot-Legris, GG Muccioli - Trends in neurosciences, 2017 - cell.com
Obesity is now a worldwide health issue. Far from being limited to weight gain, obesity is
generally associated with low-grade inflammation and with a cluster of disorders collectively …

Obesity reduces cognitive and motor functions across the lifespan

C Wang, JSY Chan, L Ren, JH Yan - Neural plasticity, 2016 - Wiley Online Library
Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In
addition to health‐related problems, obesity can also impair cognition and motor …

[HTML][HTML] Associations between modifiable risk factors and white matter of the aging brain: insights from diffusion tensor imaging studies

TM Wassenaar, K Yaffe, YD van der Werf… - Neurobiology of …, 2019 - Elsevier
There is increasing interest in factors that may modulate white matter (WM) breakdown and,
consequentially, age-related cognitive and behavioral deficits. Recent diffusion tensor …

[HTML][HTML] Obesity affects brain structure and function-rescue by bariatric surgery?

MHC Nota, D Vreeken, M Wiesmann, EO Aarts… - Neuroscience & …, 2020 - Elsevier
Obesity has a major impact on metabolic health thereby negatively affecting brain function
and structure, however mechanisms involved are not entirely understood. The increasing …

Neuroinflammation and white matter alterations in obesity assessed by diffusion basis spectrum imaging

A Samara, T Murphy, J Strain, J Rutlin, P Sun… - Frontiers in Human …, 2020 - frontiersin.org
Human obesity is associated with low-grade chronic systemic inflammation, alterations in
brain structure and function, and cognitive impairment. Rodent models of obesity show that …

White matter microstructure and cognitive decline in metabolic syndrome: a review of diffusion tensor imaging

FJ Alfaro, A Gavrieli, P Saade-Lemus, VA Lioutas… - Metabolism, 2018 - Elsevier
Metabolic syndrome is a cluster of cardiovascular risk factors defined by the presence of
abdominal obesity, glucose intolerance, hypertension and/or dyslipidemia. It is a major …

White matter microstructural variability mediates the relation between obesity and cognition in healthy adults

R Zhang, F Beyer, L Lampe, T Luck, SG Riedel-Heller… - Neuroimage, 2018 - Elsevier
Obesity has been linked with structural and functional brain changes. However, the impact of
obesity on brain and cognition in aging remains debatable, especially for white matter. We …

Body mass index and mild cognitive impairment among rural older adults in China: the moderating roles of gender and age

Y Yuan, J Li, N Zhang, P Fu, Z Jing, C Yu, D Zhao… - Bmc Psychiatry, 2021 - Springer
Background Evidence concerning the association between body mass index (BMI) and
cognitive function among older people is inconsistent. This study aimed to investigate …

Association between insomnia and cognitive performance, gray matter volume, and white matter microstructure in cognitively unimpaired adults

O Grau-Rivera, G Operto, C Falcón… - Alzheimer's research & …, 2020 - Springer
Background Mounting evidence links poor sleep quality with a higher risk of late-life
dementia. However, the structural and cognitive correlates of insomnia are still not well …

The association between body mass index, waist circumference, waist–hip ratio and cognitive disorder in older adults

Z Liu, H Yang, S Chen, J Cai… - Journal of Public Health, 2019 - academic.oup.com
Purpose To examine the association between body mass index (BMI), waist circumference
(WC), waist–hip ratio (WHR) and cognitive disorder in older adults. Methods Cross-sectional …