Biliary atresia: pathology, etiology and pathogenesis

M Vij, M Rela - Future science OA, 2020 - Taylor & Francis
Biliary atresia is a progressive fibrosing obstructive cholangiopathy of the intrahepatic and
extrahepatic biliary system, resulting in obstruction of bile flow and neonatal jaundice …

Liver fibrosis in biliary atresia

WJ Shen, G Chen, M Wang, S Zheng - World Journal of Pediatrics, 2019 - Springer
Background Biliary atresia (BA) is the most common cause of obstructive jaundice in infants.
Although the Kasai procedure has greatly improved the prognosis, most patients still need …

Role of YAP1 signaling in biliary development, repair, and disease

L Molina, K Nejak-Bowen… - Seminars in liver …, 2022 - thieme-connect.com
Yes-associated protein 1 (YAP1) is a transcriptional coactivator that activates transcriptional
enhanced associate domain transcription factors upon inactivation of the Hippo signaling …

The difference of gut microbiome in different biliary diseases in infant before operation and the changes after operation

X Sun, Y Cai, W Dai, W Jiang, W Tang - BMC pediatrics, 2022 - Springer
Background Evidence supports an association between cholestatic liver disease and
changes in microbiome composition. Nevertheless, the identification of this special type of …

Biliary atresia animal models: Is the needle in a haystack?

N Pal, PS Joy, CM Sergi - International Journal of Molecular Sciences, 2022 - mdpi.com
Biliary atresia (BA) is a progressive fibro-obliterative process with a variable degree of
inflammation involving the hepatobiliary system. Its consequences are incalculable for the …

Biliary atresia liver histopathological determinants of early post-Kasai outcome

AHP Nguyen, YHT Pham, GH Vu, MH Nguyen… - Journal of Pediatric …, 2021 - Elsevier
Background A retrospective chart review of liver histologies in Kasai biliary atresia BA
patients operated 1/2017-7/2019 at our institution was conducted to identify histologic …

Prophylactic antibiotics to prevent cholangitis in children with biliary atresia after Kasai portoenterostomy: a meta-analysis

FS Alatas, G Lazarus, MC Junaidi… - Journal of pediatric …, 2023 - journals.lww.com
Objectives: A connection between the bowel and bile ducts after the Kasai
hepatoportoenterostomy (HPE) procedure poses a risk of ascending cholangitis. There were …

Cellular therapies in pediatric liver diseases

S Vimalesvaran, J Nulty, A Dhawan - Cells, 2022 - mdpi.com
Liver transplantation is the gold standard for the treatment of pediatric end-stage liver
disease and liver based metabolic disorders. Although liver transplant is successful, its …

Development of liver inflammatory injury in biliary atresia: from basic to clinical research

S Chusilp, F Balsamo, B Li, P Vejchapipat… - Pediatric Surgery …, 2023 - Springer
Biliary atresia (BA) is a severe cholangiopathy in infants. It is characterized by inflammatory
fibro-obliteration of the intra-and extrahepatic bile ducts. Although the restoration of bile flow …

Biliary atresia: a complex hepatobiliary disease with variable gene involvement, diagnostic procedures, and prognosis

CM Sergi, S Gilmour - Diagnostics, 2022 - mdpi.com
The diagnosis of biliary atresia is still terrifying at the 3rd decade of the 21st century. In a
department of neonatal intensive care unit, parents and physicians face a challenge with a …